SCHEMBL11074667

SCHEMBL11074667

CCCC(O)OCC(C)O

nearest known ligand 0.50

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.50
HSD17B10 Q99714 1/20 0.48
MAPK1 P28482 1/20 0.39
TSHR P16473 4/20 0.38
MAPT P10636 1/20 0.36
LMNA P02545 2/20 0.32
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11654598 0.87 TDP1 (0.39) TDP1HSD17B10TSHRLMNA
SCHEMBL10823298 0.83 TSHR (0.37) TDP1HSD17B10TSHRMAPTLMNA
SCHEMBL8336558 0.82 TDP1 (0.59) TDP1HSD17B10MAPK1TSHRMAPT
SCHEMBL15923451 0.81 TDP1 (0.39) TDP1HSD17B10TSHR
SCHEMBL6144674 0.81
SCHEMBL11236220 0.79 TDP1 (0.40) TDP1HSD17B10MAPK1TSHRLMNA
SCHEMBL1206579 0.78 USP2 (0.44) TDP1MAPK1TSHRLMNAALDH1A1
SCHEMBL21872713 0.78 TDP1 (0.45) TDP1HSD17B10MAPK1TSHRMAPT
SCHEMBL2270649 0.78 TDP1 (0.61) TDP1HSD17B10MAPK1TSHRMAPT
SCHEMBL2265097 0.78 TDP1 (0.61) TDP1HSD17B10MAPK1TSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118727463-A Recyclable TPU non-woven fabric high-low temperature film and preparation method thereof 广东中鼎科技发展有限公司 2024-10-01 CN disclosed
US-4444754-A SYNERGISTIC WITH PENICILLIN BEECHAM GROUP LIMITED (GB) 1984-04-24 US disclosed
US-4435565-A ENZYME INHIBITORS BEECHAM GROUP LIMITED (GB) 1984-03-06 US disclosed
EP-0008884-B1 DERIVATIVES OF CLAVULANIC ACID, A PROCESS FOR THEIR PREPARATION AND THEIR COMPOSITIONS BEECHAM GROUP PLC (GB) 1983-08-17 EP disclosed
US-4359473-A α-Amino deoxy clavulanic acid antibacterial agents BEECHAM GROUP LIMITED (GB) 1982-11-16 US disclosed
US-4343807-A BETA-LACTAMASE INHIBITORS, BACTERICIDES, ANTIBIOTICS BEECHAM GROUP LIMITED (GB) 1982-08-10 US disclosed
US-4301168-A BACTERICIDES, BETA-LACTAMASE INHIBITORS BEECHAM GROUP LIMITED (GB) 1981-11-17 US disclosed
EP-0008884-A1 Derivatives of clavulanic acid, a process for their preparation and their compositions BEECHAM GROUP PLC (GB) 1980-03-19 EP disclosed
EP-0005014-A1 Clavulanic acid derivatives, preparation and compositions BEECHAM GROUP PLC (GB) 1979-10-31 EP disclosed