⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10783528 | 0.69 | — | — | |
| SCHEMBL9345102 | 0.67 | — | — | |
| SCHEMBL9436936 | 0.67 | — | — | |
| SCHEMBL29099762 | 0.64 | — | — | |
| SCHEMBL170153 | 0.64 | — | — | |
| SCHEMBL28598493 | 0.64 | — | — | |
| SCHEMBL7981772 | 0.62 | — | — | |
| SCHEMBL13988126 | 0.62 | — | — | |
| SCHEMBL52275 | 0.61 | — | — | |
| SCHEMBL4475934 | 0.61 | LMNA (0.62) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0034443-B1 | BETA-LACTAM ANTIBACTERIAL COMPOUNDS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BEECHAM GROUP PLC (GB) | 1984-09-26 | — | — | EP | disclosed |
| US-4407815-A | AMINO ACID DERIVATIVE ANTIBIOTICS | BEECHAM GROUP LIMITED (GB) | 1983-10-04 | — | — | US | disclosed |
| EP-0034443-A2 | Beta-lactam antibacterial compounds, their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1981-08-26 | — | — | EP | disclosed |