Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL11075014

CCC(C)COC(=O)CC(=O)O.N

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.46
MGAM O43451 1/20 0.38
GAA P10253 1/20 0.38
SI P14410 1/20 0.38
MGAM2 Q2M2H8 1/20 0.38
FFAR1 O14842 1/20 0.36
CYP3A4 P08684 1/20 0.33
TSHR P16473 1/20 0.33
ATM Q13315 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.32
ALDH1A1 P00352 1/20 0.32
CYP2D6 P10635 1/20 0.32
ELANE P08246 1/20 0.31
GPR88 Q9GZN0 3/20 0.31
MME P08473 2/20 0.31
ACE P12821 2/20 0.31
CPA1 P15085 2/20 0.31
ACE2 Q9BYF1 2/20 0.31
LDHA P00338 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9239320 0.98 MAPT (0.47) MAPTMGAMGAASIMGAM2
SCHEMBL9239317 0.98 MAPT (0.47) MAPTMGAMGAASIMGAM2
Malonic Acid SCHEMBL6827753 0.96 MAPT (0.46) MAPTMGAMGAASIMGAM2
SCHEMBL5859548 0.87 MGAM (0.50) MAPTMGAMGAASIMGAM2
SCHEMBL9239313 0.87 MGAM (0.50) MAPTMGAMGAASIMGAM2
SCHEMBL28949355 0.82 MAPT (0.37) MAPTMGAMGAASIMGAM2
SCHEMBL27870269 0.82 PRKCA (0.37) MAPTMGAMGAASIMGAM2
SCHEMBL5860234 0.82 MGAM (0.44) MAPTMGAMGAASIMGAM2
SCHEMBL28314711 0.81 MAPT (0.36) MAPTMGAMGAASIMGAM2
SCHEMBL28316466 0.81 MAPT (0.36) MAPTMGAMGAASIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4447431-A VIRICIDES, ANTIINFLAMMATORY AND SUNCREEN AGENT CIBA-GEIGY CORPORATION (US) 1984-05-08 US disclosed