Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.43 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
| ▸ | CTSE | P14091 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11761376 | 0.83 | MEN1 (0.41) | KDM1AMEN1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL11911732 | 0.82 | CYP19A1 (0.64) | CYP19A1DDB1CRBNCXCR3CTSE | |
| SCHEMBL12313146 | 0.82 | CYP19A1 (0.64) | CYP19A1DDB1CRBNCXCR3CTSE | |
| SCHEMBL11075680 | 0.82 | CYP19A1 (0.64) | CYP19A1DDB1CRBNCXCR3CTSE | |
| SCHEMBL11085029 | 0.78 | CYP19A1 (0.54) | CYP19A1KDM1A | |
| SCHEMBL10533819 | 0.78 | CYP19A1 (0.67) | CYP19A1DDB1CRBNCXCR3BACE1 | |
| SCHEMBL11088395 | 0.78 | CYP19A1 (0.54) | CYP19A1KDM1AMEN1KMT2ADDB1 | |
| SCHEMBL1552771 | 0.76 | CYP19A1 (0.69) | CYP19A1KDM1AMEN1KMT2APOLB | |
| SCHEMBL2054565 | 0.76 | CYP19A1 (0.69) | CYP19A1KDM1AMEN1KMT2APOLB | |
| SCHEMBL15196027 | 0.76 | CYP19A1 (0.69) | CYP19A1KDM1AMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435419-A | Method of treating depression using azabicyclohexanes | AMERICAN CYANAMID COMPANY (US) | 1984-03-06 | — | — | US | disclosed |
| US-4231935-A | ANXIOLYTICS AND ANALGESICS | AMERICAN CYANAMID COMPANY (US) | 1980-11-04 | — | — | US | disclosed |
| US-4196120-A | 1,2-BIS(HYDROCARBYLSULFONYLOXY OR HALO METHYL)CYCLOPROPYLBENZENE, OPTICAL ACITIVITY ANALGESICS | AMERICAN CYANAMID COMPANY (US) | 1980-04-01 | — | — | US | disclosed |
| US-4131611-A | ANXIOLYTIC, ANALGESIC | AMERICAN CYANAMID COMPANY (US) | 1978-12-26 | — | — | US | disclosed |