Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | UBE2N | P61088 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 4/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11076862 | 0.81 | KDM4E (0.51) | KDM4EGAAGLAMAPTLMNA | |
| SCHEMBL11075037 | 0.80 | KDM4E (0.42) | KDM4EGAAGLAMAPTLMNA | |
| SCHEMBL11078152 | 0.76 | KDM4E (0.51) | KDM4EGAAGLAMAPTLMNA | |
| SCHEMBL6904917 | 0.72 | KDM4E (0.67) | KDM4EGAAGLAMAPTLMNA | |
| SCHEMBL4383562 | 0.72 | MAOB (0.67) | KDM4EGAAMAPTLMNAALDH1A1 | |
| SCHEMBL29749855 | 0.72 | MAOB (0.67) | KDM4EGAAMAPTLMNAALDH1A1 | |
| SCHEMBL11075853 | 0.71 | KDM4E (0.49) | KDM4EGAAGLAMAPTLMNA | |
| SCHEMBL17716516 | 0.67 | KDM4E (0.48) | KDM4EGAAGLAMAPTLMNA | |
| SCHEMBL11075633 | 0.67 | KDM4E (0.70) | KDM4EGAAGLAMAPTLMNA | |
| SCHEMBL31006160 | 0.66 | KDM4E (0.61) | KDM4EGAAGLAMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0108036-A1 | Benzopyranones | CIBA-GEIGY AG (CH) | 1984-05-09 | — | — | EP | disclosed |