Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.49 |
| ▸ | GAA | P10253 | 7/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | GLA | P06280 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | UBE2N | P61088 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.45 |
| ▸ | PRKCI | P41743 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11078814 | 0.81 | KDM4E (0.44) | KDM4EGAAMAPTGLAHSD17B10 | |
| SCHEMBL11078823 | 0.79 | KDM4E (0.40) | KDM4EGAAMAPTGLAHSD17B10 | |
| SCHEMBL11076862 | 0.77 | KDM4E (0.51) | KDM4EGAAMAPTGLAHSD17B10 | |
| SCHEMBL11079486 | 0.76 | KDM4E (0.55) | KDM4EGAAMAPTGLAHSD17B10 | |
| SCHEMBL11078152 | 0.76 | KDM4E (0.51) | KDM4EGAAMAPTGLAHSD17B10 | |
| SCHEMBL9740799 | 0.73 | PRKCI (0.65) | CA12PRKCIHPGDCYP3A4ALOX15 | |
| SCHEMBL29749855 | 0.72 | MAOB (0.67) | KDM4EGAAMAPTHSD17B10ALDH1A1 | |
| SCHEMBL4383562 | 0.72 | MAOB (0.67) | KDM4EGAAMAPTHSD17B10ALDH1A1 | |
| SCHEMBL11075156 | 0.71 | KDM4E (0.45) | KDM4EGAAMAPTGLAHSD17B10 | |
| SCHEMBL5914907 | 0.70 | ALDH1A1 (0.53) | KDM4EGAAMAPTGLAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0108036-A1 | Benzopyranones | CIBA-GEIGY AG (CH) | 1984-05-09 | — | — | EP | disclosed |