Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.94 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
| ▸ | METAP1 | P53582 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL11075783 | 1.00 | TSHR (0.94) | TSHRLMNATDP1ALDH1A1CHRM1 | |
| Hydrochloric Acid SCHEMBL27527365 | 0.97 | TSHR (0.88) | TSHRLMNATDP1ALDH1A1CHRM1 | |
| SCHEMBL7753346 | 0.97 | TSHR (1.00) | TSHRLMNATDP1ALDH1A1CHRM1 | |
| SCHEMBL22659 | 0.97 | — | — | |
| SCHEMBL1204819 | 0.97 | — | — | |
| SCHEMBL1203795 | 0.97 | — | — | |
| SCHEMBL10787192 | 0.94 | — | — | |
| SCHEMBL10629921 | 0.94 | — | — | |
| Alcohol SCHEMBL3854623 | 0.94 | TSHR (0.94) | TSHRLMNATDP1ALDH1A1CHRM1 | |
| SCHEMBL10632079 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE31522-E | COPOLYMERS OF DIAMINE-ENDCAPPED POLYOXYETHYLENE GLYCOLS AND A DICARBOXYLIC ACID; HYDRAULIC FLUIDS; METAL WORKING | CINCINNATI MILACRON INC. (US) | 1984-02-14 | — | — | US | disclosed |
| US-4374741-A | LUBRICANTS, METAL WORKING, POLYETHER BLOCK POLYMERJ | CINCINNATI MILACRON INC. (US) | 1983-02-22 | — | — | US | disclosed |
| US-RE30885-E | Novel diamide and lubricants containing same | CINCINNATI MILACRON INC. (US) | 1982-03-23 | — | — | US | disclosed |
| US-4239635-A | METAL WORKING FLUIDS | CINCINNATI MILACRON INC. (US) | 1980-12-16 | — | — | US | disclosed |
| US-4172802-A | HIGH RESISTANCE TO HYDROLYTIC INSTABILITY | CINCINNATI MILACRON INC. (US) | 1979-10-30 | — | — | US | disclosed |