Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.94 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
| ▸ | METAP1 | P53582 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7753346 | 0.97 | TSHR (1.00) | TSHRLMNAALDH1A1TDP1CHRM1 | |
| SCHEMBL1204819 | 0.97 | — | — | |
| SCHEMBL1203795 | 0.97 | — | — | |
| SCHEMBL22659 | 0.97 | — | — | |
| SCHEMBL10629921 | 0.94 | — | — | |
| SCHEMBL10787192 | 0.94 | — | — | |
| SCHEMBL8617109 | 0.94 | — | — | |
| SCHEMBL10632079 | 0.94 | — | — | |
| SCHEMBL10786900 | 0.94 | — | — | |
| Ammonia Solution, Strong SCHEMBL11075783 | 0.94 | TSHR (0.94) | TSHRLMNAALDH1A1TDP1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050112739-A1 | Method for producing hydrocarbons and oxygen-containing compounds from biomass | SWEDISH BIOFUELS AB (SE) | 2005-05-26 | — | — | US | claimed |
| EP-0126266-B1 | LOW STRIATION POSITIVE RESIST COMPOSITION | MicroSi, Inc. (a Delaware corporation) (US) | 1990-03-21 | — | — | EP | claimed |
| EP-1697287-B1 | IMPROVEMENTS IN OR RELATING TO HYDROGENATION | EXXONMOBIL CHEM PATENTS INC (US) | 2015-08-26 | — | — | EP | disclosed |
| US-7586017-B2 | Hydrogenation | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2009-09-08 | — | — | US | disclosed |
| US-20070161829-A1 | Improvements in or relating to hydrogenation | EXXONMOBIL CHEMICAL PATENTS INC. | 2007-07-12 | — | — | US | disclosed |
| EP-1697287-A1 | IMPROVEMENTS IN OR RELATING TO HYDROGENATION | ExxonMobil Chemical Patents Inc. (US) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005058782-A1 | IMPROVEMENTS IN OR RELATING TO HYDROGENATION | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2005-06-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070161829-A1 | Improvements in or relating to hydrogenation | ADH5, ADH1C, ADH1A | TSHR 1518/4885LMNA 4769/4885ALDH1A1 897/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.