Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | PPARA | Q07869 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MMP1 | P03956 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | MMP12 | P39900 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17502748 | 1.00 | TSHR (0.59) | TSHRALDH1A1LMNAPPARATP53 | |
| SCHEMBL17502697 | 1.00 | TSHR (0.59) | TSHRALDH1A1LMNAPPARATP53 | |
| SCHEMBL17502701 | 1.00 | TSHR (0.59) | TSHRALDH1A1LMNAPPARATP53 | |
| SCHEMBL17502727 | 1.00 | TSHR (0.59) | TSHRALDH1A1LMNAPPARATP53 | |
| SCHEMBL17502703 | 1.00 | TSHR (0.59) | TSHRALDH1A1LMNAPPARATP53 | |
| SCHEMBL17502731 | 1.00 | TSHR (0.59) | TSHRALDH1A1LMNAPPARATP53 | |
| SCHEMBL17502688 | 0.98 | TSHR (0.58) | TSHRALDH1A1LMNAPPARATP53 | |
| SCHEMBL17502694 | 0.94 | TSHR (0.57) | TSHRALDH1A1LMNAPPARATP53 | |
| SCHEMBL17502750 | 0.87 | ALDH1A1 (0.55) | TSHRALDH1A1LMNAPPARAKDM4E | |
| SCHEMBL17502726 | 0.87 | SMN1; SMN2 (0.55) | TSHRALDH1A1LMNAPPARATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9738736-B2 | Combined internal donor system for Ziegler-Natta polyolefin catalysts and methods of making and using same | W. R. GRACE & CO.-CONN (US) | 2017-08-22 | — | — | US | claimed |
| WO-2016025194-A1 | COMBINED INTERNAL DONOR SYSTEM FOR ZIEGLER-NATTA POLYOLEFIN CATALYSTS AND METHODS OF MAKING AND USING SAME | BASF CORPORATION (US) | 2016-02-18 | — | — | WO | claimed |
| US-20160046740-A1 | COMBINED INTERNAL DONOR SYSTEM FOR ZIEGLER-NATTA POLYOLEFIN CATALYSTS AND METHODS OF MAKING AND USING SAME | W. R. GRACE & CO.-CONN. | 2016-02-18 | — | — | US | claimed |
| US-9738736-B2 | Combined internal donor system for Ziegler-Natta polyolefin catalysts and methods of making and using same | W. R. GRACE & CO.-CONN (US) | 2017-08-22 | — | — | US | disclosed |
| US-20160046740-A1 | COMBINED INTERNAL DONOR SYSTEM FOR ZIEGLER-NATTA POLYOLEFIN CATALYSTS AND METHODS OF MAKING AND USING SAME | W. R. GRACE & CO.-CONN. | 2016-02-18 | — | — | US | disclosed |
| WO-2016025194-A1 | COMBINED INTERNAL DONOR SYSTEM FOR ZIEGLER-NATTA POLYOLEFIN CATALYSTS AND METHODS OF MAKING AND USING SAME | BASF CORPORATION (US) | 2016-02-18 | — | — | WO | disclosed |
| US-4429035-A | NONSILVER PHOTOGRAPHY, OXIDATIVE COUPLING | FUJI PHOTO FILM CO., LTD. (JP) | 1984-01-31 | — | — | US | disclosed |