Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HRH1 | P35367 | 2/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL67968 | 0.91 | — | — | |
| Water SCHEMBL28098685 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL28181815 | 0.88 | — | — | |
| SCHEMBL27968456 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL7937814 | 0.88 | TSHR (0.37) | TSHRALDH1A1MAPTLMNAALOX12 | |
| SCHEMBL9718210 | 0.88 | TSHR (0.37) | TSHRALDH1A1MAPTLMNAALOX12 | |
| Ammonia Solution, Strong SCHEMBL28586237 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL5702841 | 0.88 | TSHR (0.37) | TSHRALDH1A1MAPTLMNAALOX12 | |
| Fluoride SCHEMBL29655462 | 0.88 | — | — | |
| SCHEMBL28535293 | 0.85 | TSHR (0.36) | TSHRALDH1A1MAPTLMNAALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4490538-A | Enlarged-hetero-ring prostacyclin analogs | THE UPJOHN COMPANY (US) | 1984-12-25 | — | — | US | disclosed |
| US-4490537-A | Enlarged-hetero-ring prostacyclin analogs | THE UPJOHN COMPANY (US) | 1984-12-25 | — | — | US | disclosed |
| US-4490548-A | Enlarged-hetero-ring prostacyclin analogs | THE UPJOHN COMPANY (US) | 1984-12-25 | — | — | US | disclosed |
| US-4490549-A | Enlarged-hetero-ring prostacyclin analogs | THE UPJOHN COMPANY (US) | 1984-12-25 | — | — | US | disclosed |
| US-4058564-A | PROSTAGLANDINS; HYPOTENSIVE, LABOR INDUCERS, ANTISECRETORY | THE UPJOHN COMPANY (US) | 1977-11-15 | — | — | US | disclosed |