SCHEMBL9718210

SCHEMBL9718210

C[SiH2]C.C[SiH2]c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.37
ACHE P22303 2/20 0.37
LMNA P02545 1/20 0.37
ALOX12 P18054 1/20 0.37
LTA4H P09960 2/20 0.35
MAPT P10636 1/20 0.35
HPGD P15428 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
MGLL Q99685 1/20 0.35
HSD17B10 Q99714 1/20 0.35
ALDH1A1 P00352 3/20 0.33
CA4 P22748 2/20 0.32
TP53 P04637 1/20 0.32
MAPK1 P28482 1/20 0.30
APOBEC3A P31941 1/20 0.30
APOBEC3G Q9HC16 1/20 0.30
CA1 P00915 2/20 0.30
CA2 P00918 2/20 0.30
CA9 Q16790 2/20 0.30
TDP1 Q9NUW8 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL67968 0.97
SCHEMBL7785325 0.94 TSHR (0.35) TSHRACHELMNAALOX12LTA4H
Ammonia Solution, Strong SCHEMBL28586237 0.93
Fluoride SCHEMBL29655462 0.93
Hydrochloric Acid SCHEMBL7937814 0.93 TSHR (0.37) TSHRACHELMNAALOX12LTA4H
Hydrochloric Acid SCHEMBL5702841 0.93 TSHR (0.37) TSHRACHELMNAALOX12LTA4H
SCHEMBL28535293 0.90 TSHR (0.36) TSHRACHELMNAALOX12LTA4H
Hydrochloric Acid SCHEMBL5165959 0.90 TSHR (0.35) TSHRACHELMNAALOX12LTA4H
Trimethylammonium SCHEMBL11075798 0.88 TSHR (0.36) TSHRACHELMNAALOX12LTA4H
SCHEMBL4230907 0.83 TDP1 (0.33) TSHRACHELMNAALOX12TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116891572-A Metal removing method for polysilane compound 日产化学株式会社 2023-10-17 CN disclosed
EP-0349898-B1 PARTICULATE MATERIAL COMPRISING A PLATINUM-CONTAINING HYDROSILYLATION CATALYST AND A DIORGANOPOLYSILANE TORAY SILICONE COMPANY, LIMITED (JP) 1992-08-26 EP disclosed
US-5015716-A Platinum catalyst in a polydiorganosilane for hydrosilation TORAY SILICONE COMPANY, LIMITED (JP) 1991-05-14 US disclosed
EP-0349898-A2 Particulate material comprising a platinum-containing hydrosilylation catalyst and a diorganopolysilane TORAY SILICONE COMPANY, LIMITED (JP) 1990-01-10 EP disclosed