Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11075310 | 0.89 | MAPT (0.59) | MAPTKMT2AMEN1CYP3A4CYP19A1 | |
| SCHEMBL11081070 | 0.88 | MAPT (0.76) | MAPTKMT2AMEN1CYP3A4CYP19A1 | |
| SCHEMBL5364455 | 0.87 | MAPT (0.77) | MAPTKMT2AMEN1CYP3A4CYP19A1 | |
| SCHEMBL11097860 | 0.87 | MAPT (0.54) | MAPTKMT2AMEN1CYP3A4CYP19A1 | |
| SCHEMBL11129336 | 0.85 | MAPT (0.52) | MAPTKMT2AMEN1CYP3A4CYP19A1 | |
| SCHEMBL10362204 | 0.84 | MAPT (0.61) | MAPTKMT2AMEN1CYP3A4CYP19A1 | |
| SCHEMBL10733485 | 0.83 | MAPT (0.60) | MAPTKMT2AMEN1CYP3A4CYP19A1 | |
| SCHEMBL10930807 | 0.81 | MAPT (0.67) | MAPTKMT2AMEN1CYP3A4CYP19A1 | |
| SCHEMBL11073325 | 0.80 | CYP24A1 (0.57) | KMT2AMEN1CYP3A4CYP19A1 | |
| SCHEMBL10363694 | 0.78 | MAPT (0.63) | MAPTKMT2AMEN1CYP3A4CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0125409-A2 | 4-Azolyl-pentanenitriles, process for their preparation and biocides containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1984-11-21 | — | — | EP | claimed |
| EP-0125409-A2 | 4-Azolyl-pentanenitriles, process for their preparation and biocides containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1984-11-21 | — | — | EP | disclosed |