SCHEMBL5364455

SCHEMBL5364455

CC(C)(C)C(=O)C(Cc1ccc(Cl)cc1)n1cncn1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.77
KMT2A Q03164 4/20 0.60
MEN1 O00255 3/20 0.60
CYP3A4 P08684 3/20 0.59
CYP19A1 P11511 5/20 0.52
TSHR P16473 1/20 0.48
CYP24A1 Q07973 1/20 0.46
HSP90AA1 P07900 2/20 0.45
POLB P06746 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
ALDH1A1 P00352 1/20 0.43
RAB9A P51151 1/20 0.43
ATM Q13315 1/20 0.43
PPARG P37231 1/20 0.41
ADORA3 P0DMS8 1/20 0.39
CHRM1 P11229 1/20 0.39
SLC6A2 P23975 1/20 0.39
SLC6A4 P31645 1/20 0.39
ADRA1A P35348 1/20 0.39
SLC6A3 Q01959 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10363694 0.90 MAPT (0.63) MAPTKMT2AMEN1CYP3A4CYP19A1
SCHEMBL10362204 0.89 MAPT (0.61) MAPTKMT2AMEN1CYP3A4CYP19A1
SCHEMBL10733485 0.88 MAPT (0.60) MAPTKMT2AMEN1CYP3A4CYP19A1
SCHEMBL11366095 0.87 MAPT (0.77) MAPTKMT2AMEN1CYP3A4CYP19A1
SCHEMBL11076165 0.87 MAPT (0.59) MAPTKMT2AMEN1CYP3A4CYP19A1
SCHEMBL9824981 0.87 MAPT (1.00) MAPTKMT2AMEN1CYP3A4CYP19A1
SCHEMBL10930807 0.86 MAPT (0.67) MAPTKMT2AMEN1CYP3A4CYP19A1
SCHEMBL23529438 0.85 MAPT (0.67) MAPTKMT2AMEN1CYP3A4CYP19A1
SCHEMBL29767719 0.85 MAPT (0.67) MAPTKMT2AMEN1CYP3A4CYP19A1
SCHEMBL23564008 0.84 MAPT (0.67) MAPTKMT2AMEN1CYP3A4CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10106408-B2 Method for conducting deracemization using Taylor flow and a device therefor UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY (KR) 2018-10-23 US claimed
US-20170081188-A1 METHOD FOR CONDUCTING DERACEMIZATION USING TAYLOR FLOW AND A DEVICE THEREFOR UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY (KR) 2017-03-23 US claimed
CN-117658934-A Preparation method of high-purity chlorazolone 辽宁优创植物保护有限公司 2024-03-08 CN disclosed
CN-111777565-B Preparation method of chlorzodone 江苏七洲绿色化工股份有限公司 2022-03-18 CN disclosed
CN-111777565-A Preparation method of chlorzodone 江苏七洲绿色化工股份有限公司 2020-10-16 CN disclosed
US-10106408-B2 Method for conducting deracemization using Taylor flow and a device therefor UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY (KR) 2018-10-23 US disclosed
US-20170081188-A1 METHOD FOR CONDUCTING DERACEMIZATION USING TAYLOR FLOW AND A DEVICE THEREFOR UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY (KR) 2017-03-23 US disclosed
US-7292389-B2 Circular extinction contrast imaging microscope UNIVERSITY OF WASHINGTON (US) 2007-11-06 US disclosed
US-20050134687-A1 Circular extinction contrast imaging microscope THE UNIVERSITY OF WASHINGTON (US) 2005-06-23 US disclosed
EP-0097881-B1 SUBSTITUTED AZOLYL KETONES AND ALCOHOLS BAYER AG (DE) 1990-08-29 EP disclosed
US-4945101-A Fungicidal novel hydroxyalkynyl-azolyl derivatives BAYER AKTIENGESELLSCHAFT (DE) 1990-07-31 US disclosed
EP-0031911-A2 Substituted triazolylmethyl-tert.-butyl-ketones, process for their preparation and their use as plant protecting agents as well as intermediates BAYER AG (DE) 1981-07-15 EP disclosed
EP-0028363-A1 Entriazoles, their preparation, their use as fungicides, and means therefor BASF Aktiengesellschaft (DE) 1981-05-13 EP disclosed
EP-0024538-A1 1,2,4-Triazolyl-enol ethers, process for preparing them and their use as fungicides BAYER AG (DE) 1981-03-11 EP disclosed
US-4243405-A HYDROXYALKYLTRIAZOLES AND DERIVATIVES, PLANT GROWTH REGULATORS IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1981-01-06 US disclosed
EP-0019131-A1 Fluorinated derivatives of 1-triazolyl butane, process for their preparation and their use as fungicides BAYER AG (DE) 1980-11-26 EP disclosed
EP-0016323-A1 1-Allyltriazole derivatives, process for their preparation and their use as plant protecting agents BAYER AG (DE) 1980-10-01 EP disclosed
EP-0015639-A2 Enantiomers of triazole compounds, a process for preparing them, their use as plant fungicides and growth regulating agents and compositions containing them IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1980-09-17 EP disclosed
EP-0015387-A2 1-Vinyltriazole derivatives, process for their preparation and their use as growth regulating agents and fungicides BAYER AG (DE) 1980-09-17 EP disclosed
US-4205075-A Processes and composition for combating fungi IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1980-05-27 US disclosed