Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.35 |
| ▸ | RAB9A | P51151 | 6/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11078807 | 0.89 | NPC1 (0.35) | NPC1RAB9AKDM4EPOLBALDH1A1 | |
| SCHEMBL11077430 | 0.89 | GAA (0.39) | NPC1RAB9AKDM4EPOLBALDH1A1 | |
| SCHEMBL4824520 | 0.88 | MAOB (0.40) | NPC1RAB9AKDM4EALDH1A1MAPT | |
| SCHEMBL21192287 | 0.87 | MEN1 (0.33) | NPC1RAB9AKDM4EPOLBMAPT | |
| SCHEMBL14570420 | 0.84 | S1PR1 (0.38) | ALDH1A1KMT2AGAAMEN1ALOX5 | |
| SCHEMBL10752939 | 0.82 | KDM4E (0.49) | NPC1RAB9AKDM4EPOLBALDH1A1 | |
| SCHEMBL9374944 | 0.80 | MAOB (0.39) | NPC1RAB9AKDM4EPOLBALDH1A1 | |
| SCHEMBL4822395 | 0.80 | MAOB (0.36) | KDM4EALDH1A1MAPTKMT2AGAA | |
| SCHEMBL4820165 | 0.79 | MAOB (0.36) | ALDH1A1SMN1; SMN2LMNAKMT2AGAA | |
| SCHEMBL4825189 | 0.78 | MAOB (0.38) | NPC1RAB9AKDM4EPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4481315-A | LACQUERS | CIBA-GEIGY CORPORATION (US) | 1984-11-06 | — | — | US | disclosed |
| EP-0010516-B1 | POLYALKYLPIPERIDINE DERIVATIVES, THEIR APPLICATION AS LIGHT STABILISERS AND POLYMERS STABILISED THEREWITH | CIBA-GEIGY AG (CH) | 1982-07-14 | — | — | EP | disclosed |
| US-4289686-A | FOR LACQUERS | CIBA-GEIGY CORPORATION (US) | 1981-09-15 | — | — | US | disclosed |
| EP-0010516-A1 | Polyalkylpiperidine derivatives, their application as light stabilisers and polymers stabilised therewith | CIBA-GEIGY AG (CH) | 1980-04-30 | — | — | EP | disclosed |