SCHEMBL4825189

SCHEMBL4825189

CC1(C)CC(OC(=O)CCc2cc(-n3nc4ccccc4n3)c(O)c(C(C)(C)C)c2)CC(C)(C)N1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.38
MAOA P21397 2/20 0.38
GAA P10253 7/20 0.38
ACHE P22303 1/20 0.37
KMT2A Q03164 3/20 0.35
MEN1 O00255 2/20 0.35
NPC1L1 Q9UHC9 1/20 0.34
ALDH1A1 P00352 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
LMNA P02545 1/20 0.33
AGTR1 P30556 1/20 0.33
HTT P42858 1/20 0.33
KDM4E B2RXH2 2/20 0.32
POLB P06746 2/20 0.32
GLA P06280 1/20 0.32
HPGD P15428 1/20 0.32
EZH2 Q15910 1/20 0.32
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4824520 0.90 MAOB (0.40) MAOBMAOAGAAACHEKMT2A
SCHEMBL4817450 0.89 MAOB (0.34) MAOBMAOAGAAACHEKMT2A
SCHEMBL11077430 0.88 GAA (0.39) GAANPC1L1ALDH1A1SMN1; SMN2LMNA
SCHEMBL9374944 0.88 MAOB (0.39) MAOBMAOAGAAACHEKMT2A
SCHEMBL9228813 0.85 MAOB (0.42) MAOBMAOAGAAACHEKMT2A
SCHEMBL4821028 0.84 MAOB (0.38) MAOBMAOAGAAACHEKMT2A
SCHEMBL10348415 0.84 GAA (0.46) MAOBMAOAGAAACHEKMT2A
SCHEMBL9374601 0.82 MAOB (0.36) MAOBMAOAGAAACHEKMT2A
SCHEMBL31349925 0.82 GAA (0.43) MAOBMAOAGAAACHEKMT2A
SCHEMBL10135978 0.81 ALOX5 (0.44) MAOBMAOAGAAACHEKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030074833-A1 Benzotriazole/hals molecular combinations and compositions stabilized therewith CIBA SPECIALTY CHEMCIALS CORP. 2003-04-24 US claimed
US-7419513-B2 Hindered amine light stabilizers (HALS); for thermoset/thermoplastic resins, photographic applications, pigmented/dyed polypropylene, polyamide/polyester fibers, and for white, dyed, dipped, unscented/scented candle wax against discoloration and fading CIBA SPECIALTY CHEMICALS CORPORATION (US) 2008-09-02 US disclosed
US-20050043543-A1 Benzotriazole/HALS molecular combinations and compositions stabilized therewith WOOD MERVIN G (US) 2005-02-24 US disclosed
US-6846929-B2 Benzotriazole/hals molecular combinations and compositions stabilized therewith CIBA SPECIALTY CHEMICALS CORPORATION (US) 2005-01-25 US disclosed
US-20030074833-A1 Benzotriazole/hals molecular combinations and compositions stabilized therewith CIBA SPECIALTY CHEMCIALS CORP. 2003-04-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030074833-A1 Benzotriazole/hals molecular combinations and compositions stabilized therewith TAS1R1, TAS1R2, BRWD1 MAOB 972/4885MAOA 697/4885GAA 751/4885
US-20050043543-A1 Benzotriazole/HALS molecular combinations and compositions stabilized therewith BRWD1, TAS1R2, TAS1R1 MAOB 787/4885MAOA 690/4885GAA 1240/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.