Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 3/20 | 0.39 |
| ▸ | DRD3 | P35462 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11688495 | 0.74 | CYP1A2 (0.57) | CYP1A2CYP2C19NPSR1MAPTRORC | |
| SCHEMBL11558653 | 0.72 | CYP1A2 (0.38) | CYP1A2CYP2C19NPSR1MAPTCHRNB4 | |
| SCHEMBL11563044 | 0.71 | CYP1A2 (0.46) | CYP1A2CYP2C19NPSR1MAPTCHRNB4 | |
| SCHEMBL8236464 | 0.70 | CYP1A2 (0.63) | CYP1A2CYP2C19NPSR1MAPTCHRNB4 | |
| SCHEMBL11560597 | 0.69 | CYP1A2 (0.44) | CYP1A2CYP2C19NPSR1MAPTCHRNB4 | |
| SCHEMBL11562919 | 0.68 | CYP1A2 (0.40) | CYP1A2CYP2C19NPSR1MAPTCHRNB4 | |
| SCHEMBL4310997 | 0.68 | CYP1A2 (0.58) | CYP1A2CYP2C19NPSR1MAPTCHRNB4 | |
| SCHEMBL8434239 | 0.68 | KDM4E (0.48) | CYP1A2CYP2C19NPSR1MAPTCHRNB4 | |
| SCHEMBL11560613 | 0.67 | CYP1A2 (0.39) | CYP1A2CYP2C19NPSR1MAPTCHRNB4 | |
| SCHEMBL11563883 | 0.67 | CYP1A2 (0.39) | CYP1A2CYP2C19NPSR1MAPTCHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4487719-A | Azo dyes from substituted 3-amino-pyridines with aniline, tetrahydroquinoline and benzomorpholine couplers | EASTMAN KODAK COMPANY (US) | 1984-12-11 | — | — | US | disclosed |