Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.37 |
| ▸ | RORC | P51449 | 5/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11562423 | 0.87 | RIPK1 (0.39) | NPSR1RIPK1RORCNR3C2NPC1 | |
| SCHEMBL11555685 | 0.85 | ALDH1A1 (0.37) | CYP2C19NR3C2MAPTCYP3A4CYP2D6 | |
| SCHEMBL11557947 | 0.84 | NR3C2 (0.42) | RORCNR3C2L3MBTL1 | |
| SCHEMBL11560186 | 0.84 | NR3C2 (0.42) | NPSR1NR3C2MAPTHTT | |
| SCHEMBL11559425 | 0.83 | NR3C2 (0.40) | NPSR1NR3C2L3MBTL1 | |
| SCHEMBL11557151 | 0.83 | GAA (0.40) | NR3C2MAPTNPC1CYP3A4 | |
| SCHEMBL11557741 | 0.82 | NPC1 (0.36) | RORCNR3C2TDP1NPC1 | |
| SCHEMBL11561537 | 0.81 | NR3C2 (0.43) | NPSR1NR3C2MAPTNPC1HTT | |
| SCHEMBL11558641 | 0.78 | SIRT1 (0.38) | CYP1A2CYP2C19NPSR1RORCMAPT | |
| SCHEMBL11076395 | 0.72 | CYP1A2 (0.48) | CYP1A2CYP2C19NPSR1RIPK1CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4134974-A | Imidazo[5,1-c][1,4]benzoxazin-1-one | CARLO ERBA S. P. A. (IT) | 1979-01-16 | — | — | US | disclosed |