Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 11/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.64 |
| ▸ | LMNA | P02545 | 4/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.64 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.64 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.64 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.64 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.64 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12029054 | 1.00 | CYP19A1 (0.73) | CYP19A1CYP3A4LMNAMAPTCYP2C9 | |
| SCHEMBL23383834 | 1.00 | CYP19A1 (0.73) | CYP19A1CYP3A4LMNAMAPTCYP2C9 | |
| SCHEMBL8981421 | 1.00 | CYP19A1 (0.73) | CYP19A1CYP3A4LMNAMAPTCYP2C9 | |
| SCHEMBL524063 | 1.00 | CYP19A1 (0.73) | CYP19A1CYP3A4LMNAMAPTCYP2C9 | |
| Fluoride SCHEMBL29039527 | 0.99 | CYP19A1 (0.71) | CYP19A1CYP3A4LMNAMAPTCYP2C9 | |
| SCHEMBL14645179 | 0.91 | CYP19A1 (0.73) | CYP19A1CYP3A4LMNAMAPTCYP2C9 | |
| SCHEMBL4220878 | 0.91 | CYP19A1 (0.73) | CYP19A1CYP3A4LMNAMAPTCYP2C9 | |
| SCHEMBL2705268 | 0.91 | CYP19A1 (0.73) | CYP19A1CYP3A4LMNAMAPTCYP2C9 | |
| SCHEMBL4218877 | 0.91 | CYP19A1 (0.73) | CYP19A1CYP3A4LMNAMAPTCYP2C9 | |
| SCHEMBL11774599 | 0.90 | CYP19A1 (0.71) | CYP19A1CYP3A4LMNAMAPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4472393-A | ANTIINFLAMMATORY AGENTS | SCHERING CORPORATION (US) | 1984-09-18 | — | — | US | disclosed |