Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 11/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.64 |
| ▸ | LMNA | P02545 | 4/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.64 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.64 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.64 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.64 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.64 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11076539 | 1.00 | CYP19A1 (0.73) | CYP19A1CYP3A4LMNAMAPTCYP2C9 | |
| SCHEMBL12029054 | 1.00 | CYP19A1 (0.73) | CYP19A1CYP3A4LMNAMAPTCYP2C9 | |
| SCHEMBL23383834 | 1.00 | CYP19A1 (0.73) | CYP19A1CYP3A4LMNAMAPTCYP2C9 | |
| SCHEMBL8981421 | 1.00 | CYP19A1 (0.73) | CYP19A1CYP3A4LMNAMAPTCYP2C9 | |
| Fluoride SCHEMBL29039527 | 0.99 | CYP19A1 (0.71) | CYP19A1CYP3A4LMNAMAPTCYP2C9 | |
| SCHEMBL14645179 | 0.91 | CYP19A1 (0.73) | CYP19A1CYP3A4LMNAMAPTCYP2C9 | |
| SCHEMBL4220878 | 0.91 | CYP19A1 (0.73) | CYP19A1CYP3A4LMNAMAPTCYP2C9 | |
| SCHEMBL2705268 | 0.91 | CYP19A1 (0.73) | CYP19A1CYP3A4LMNAMAPTCYP2C9 | |
| SCHEMBL4218877 | 0.91 | CYP19A1 (0.73) | CYP19A1CYP3A4LMNAMAPTCYP2C9 | |
| SCHEMBL11774599 | 0.90 | CYP19A1 (0.71) | CYP19A1CYP3A4LMNAMAPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 545 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4724040-A1 | TREATMENT OF PSORIASIS | TRADOVA (PTY) LTD (ZA) | 2026-04-15 | — | — | EP | claimed |
| CN-119125361-A | Rapid detection method for 27 steroid hormones in mangrove plants | 中国科学院南海海洋研究所 | 2024-12-13 | — | — | CN | claimed |
| WO-2024252238-A1 | TREATMENT OF PSORIASIS | HASSEN, Mohammed, Ameen (ZA) | 2024-12-12 | — | — | WO | claimed |
| CN-118858479-A | Kit for simultaneously detecting 90 steroid hormones and metabolites thereof in urine sample, detection method and sample pretreatment method | 中国疾病预防控制中心环境与健康相关产品安全所 | 2024-10-29 | — | — | CN | claimed |
| CN-118271382-A | New process for preparing series corticosteroids such as prednisolone by using progesterone | 天津药业研究院股份有限公司 | 2024-07-02 | — | — | CN | claimed |
| CN-118271381-A | New process for preparing prednisone and other series corticosteroids from progesterone | 天津药业研究院股份有限公司 | 2024-07-02 | — | — | CN | claimed |
| US-20240029838-A1 | METHODS FOR TREATING AND PREVENTING SYMPTOMS OF ASTHMA WITH A CORTICOSTEROID PHARMACEUTICAL COMPOSITION | ASTRAZENECA UK LIMITED (GB) | 2024-01-25 | — | — | US | claimed |
| EP-3604322-B1 | LACTULOSE GLYCOSIDE COMPOUND AND PREPARATION METHOD AND USE THEREOF | FRUITHY HOLDINGS LTD (CN) | 2023-10-18 | — | — | EP | claimed |
| WO-2022204827-A1 | APPLICATION OF HALCINONIDE AND DERIVATIVES THEREOF FOR PREPARING DRUG TREATING AND/OR PREVENTING CEREBROVASCULAR DISEASE | 兰州大学 | 2022-10-06 | — | — | WO | claimed |
| CN-112997256-A | Methods of treating and preventing asthma symptoms using corticosteroid pharmaceutical compositions | 阿斯利康(英国)有限公司 | 2021-06-18 | — | — | CN | claimed |
| US-4867913-A | INTERMEDIATES FOR CORTICOIDS | KURARAY CO., LTD. (JP) | 1989-09-19 | — | — | US | claimed |
| EP-0117266-B1 | 12-ALPHA-SUBSTITUTED PREGNA-1,4-DIENE-3,20-DIONES | KURARAY CO., LTD. (JP) | 1986-10-08 | — | — | EP | claimed |
| US-4472393-A | ANTIINFLAMMATORY AGENTS | SCHERING CORPORATION (US) | 1984-09-18 | — | — | US | claimed |
| EP-0117266-A1 | 12-Alpha-substituted pregna-1,4-diene-3,20-diones | KURARAY CO., LTD. (JP) | 1984-09-05 | — | — | EP | claimed |
| EP-0057401-B1 | AROMATIC HETEROCYCLIC ESTERS OF STEROIDS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCHERING CORPORATION (US) | 1984-08-01 | — | — | EP | claimed |
| EP-0095894-A2 | 6 Alpha-methylprednisolone derivatives | OHTA SEIYAKU KABUSHIKI KAISHA. (JP) | 1983-12-07 | — | — | EP | claimed |
| EP-0034365-B1 | PROCESS FOR THE PREPARATION OF 3,20-DIOXO-PREGN-4-ENE AND/OR 3,20-DIOXO-PREGNA-1,4-DIENE | HENKEL CORPORATION (a Delaware corp.) (US) | 1983-06-29 | — | — | EP | claimed |
| EP-0057401-A1 | Aromatic heterocyclic esters of steroids, their preparation and pharmaceutical compositions containing them | SCHERING CORPORATION (US) | 1982-08-11 | — | — | EP | claimed |
| EP-0034365-A2 | Process for the preparation of 3,20-dioxo-pregn-4-ene and/or 3,20-dioxo-pregna-1,4-diene | HENKEL CORPORATION (a Delaware corp.) (US) | 1981-08-26 | — | — | EP | claimed |
| US-4252732-A | HYDROLYSIS OF THE ANIL REACTION PRODUCT OF 3-OXO-PREGN-4-ENE OR 1,4-DIENE AND A 3,5-DIALKYL ORTHOQUINONE TO OBTAIN THE DIKETONE | HENKEL CORPORATION (US) | 1981-02-24 | — | — | US | claimed |