Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 4/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | APEX1 | P27695 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CASP6 | P55212 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | PKLR | P30613 | 6/20 | 0.43 |
| ▸ | PGAM1 | P18669 | 4/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11515026 | 0.84 | ALDH1A1 (0.56) | BCL2MCL1ALDH1A1CYP3A4TSHR | |
| SCHEMBL7435273 | 0.82 | BCL2 (0.63) | BCL2MCL1ALDH1A1CYP3A4TSHR | |
| SCHEMBL11076558 | 0.78 | BCL2 (0.53) | BCL2MCL1ALDH1A1CYP3A4MAPT | |
| SCHEMBL11775580 | 0.77 | ALDH1A1 (0.54) | BCL2MCL1ALDH1A1CYP3A4TSHR | |
| SCHEMBL10355812 | 0.76 | ALDH1A1 (0.67) | BCL2MCL1ALDH1A1CYP3A4TSHR | |
| SCHEMBL8204960 | 0.75 | MAPT (0.50) | BCL2MCL1ALDH1A1CYP3A4TSHR | |
| SCHEMBL11424411 | 0.73 | ALDH1A1 (0.62) | BCL2MCL1ALDH1A1CYP3A4TSHR | |
| SCHEMBL11515022 | 0.72 | ALDH1A1 (0.57) | BCL2MCL1ALDH1A1CYP3A4TSHR | |
| SCHEMBL10908174 | 0.72 | MAPT (0.54) | BCL2MCL1ALDH1A1CYP3A4TSHR | |
| SCHEMBL29543750 | 0.72 | BCL2 (0.60) | BCL2MCL1ALDH1A1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0069910-B1 | PROCESS FOR THE PREPARATION OF 1-HYDROXY-4-AMINO-5(8)-NITRO-ANTHRAQUINONE | BAYER AG (DE) | 1984-11-07 | — | — | EP | disclosed |
| US-4424160-A | Process for the preparation of 1-hydroxy-4-amino-5(8)-nitroanthraquinone | BAYER AKTIENGESELLSCHAFT (DE) | 1984-01-03 | — | — | US | disclosed |
| EP-0069910-A1 | Process for the preparation of 1-hydroxy-4-amino-5(8)-nitro-anthraquinone | BAYER AG (DE) | 1983-01-19 | — | — | EP | disclosed |