Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | BCHE | P06276 | 3/20 | 0.58 |
| ▸ | ACHE | P22303 | 3/20 | 0.58 |
| ▸ | BACE1 | P56817 | 3/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | SORD | Q00796 | 1/20 | 0.51 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.51 |
| ▸ | METAP1 | P53582 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3319562 | 0.85 | KCNH2 (0.73) | GAAMAPTBCHEACHEBACE1 | |
| SCHEMBL29381819 | 0.85 | KCNH2 (0.73) | GAAMAPTBCHEACHEBACE1 | |
| SCHEMBL22495402 | 0.83 | NPC1 (0.56) | MAPTALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL29857922 | 0.83 | PLD1 (0.73) | GAAMAPTKCNH2PLD1ALDH1A1 | |
| SCHEMBL21353591 | 0.83 | — | — | |
| SCHEMBL15800694 | 0.83 | PLD1 (0.73) | GAAMAPTKCNH2PLD1ALDH1A1 | |
| SCHEMBL1126513 | 0.83 | HTR1A (0.58) | GAAMAPTKCNH2PLD1ALDH1A1 | |
| SCHEMBL2232397 | 0.83 | KCNH2 (0.57) | GAAMAPTKCNH2PLD1ALDH1A1 | |
| SCHEMBL16994742 | 0.83 | KDM4E (0.62) | GAAMAPTACHEBACE1KCNH2 | |
| SCHEMBL26597976 | 0.80 | MAPT (0.69) | GAAMAPTALDH1A1KDM4EGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4456605-A | FUNGICIDES, BACTERICIDES | JANSSEN PHARMACEUTICA N.V. (BE) | 1984-06-26 | — | — | US | disclosed |
| US-4402957-A | FUNGICIDES, BACTERICIDES | JANSSEN PHARMACEUTICA N.V. (BE) | 1983-09-06 | — | — | US | disclosed |
| EP-0007696-B1 | HETEROCYCLIC DERIVATIVES OF (4-(PIPERAZIN-1-YL-PHENYLOXYMETHYL)-1.3.-DIOXOLAN-2-YLMETHYL)-1H-IMIDAZOLES AND -1H-1.2.4-TRIAZOLES, THEIR PREPARATION AND USE AS FUNGICIDES AND BACTERICIDES | JANSSEN PHARMACEUTICA N.V. (BE) | 1982-10-27 | — | — | EP | disclosed |
| US-4287195-A | USEFUL AS BACTERICIDES AND FUNGICIDES | JANSSEN PHARMACEUTICA, N.V. (BE) | 1981-09-01 | — | — | US | disclosed |
| EP-0007696-A1 | Heterocyclic derivatives of (4-(piperazin-1-yl-phenyloxymethyl)-1.3.-dioxolan-2-ylmethyl)-1H-imidazoles and -1H-1.2.4-triazoles, their preparation and use as fungicides and bactericides | JANSSEN PHARMACEUTICA N.V. (BE) | 1980-02-06 | — | — | EP | disclosed |