Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | MPO | P05164 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25060900 | 0.80 | GAA (0.56) | KDM4EMPOGAASMN1; SMN2HIF1A | |
| SCHEMBL9313941 | 0.80 | KDM4E (0.47) | KDM4EMPOGAASMN1; SMN2HIF1A | |
| SCHEMBL9313474 | 0.77 | SELL (0.58) | KDM4EMPOGAASMN1; SMN2HIF1A | |
| SCHEMBL11143960 | 0.76 | GAA (0.52) | KDM4EMPOGAASMN1; SMN2HIF1A | |
| SCHEMBL8605862 | 0.75 | HDAC1 (0.50) | KDM4EGAASMN1; SMN2HDAC1NSD2 | |
| SCHEMBL3517151 | 0.73 | SELL (0.58) | KDM4EGAASMN1; SMN2HIF1AHDAC1 | |
| SCHEMBL11049772 | 0.73 | HDAC6 (0.42) | KDM4EMPOGAASMN1; SMN2HIF1A | |
| SCHEMBL25060909 | 0.72 | GAA (0.50) | KDM4EMPOGAASMN1; SMN2HIF1A | |
| SCHEMBL6376194 | 0.71 | KDM4E (0.44) | KDM4EGAASMN1; SMN2HDAC1NSD2 | |
| SCHEMBL28610455 | 0.71 | SELL (0.56) | KDM4EGAASMN1; SMN2HIF1AHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4448730-A | ANTITUMOR AGENTS | RIET BARTHOLOMEUS VAN T | 1984-05-15 | — | — | US | disclosed |
| US-4448730-A | ANTITUMOR AGENTS | RIET BARTHOLOMEUS VAN T | 1984-05-15 | — | — | US | disclosed |