Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9313956 | 0.76 | CYP3A4 (0.52) | HDAC6KDM4EGAAMAPTSMN1; SMN2 | |
| SCHEMBL7896049 | 0.75 | FFAR1 (0.44) | KDM4EGAALMNATDP1FFAR1 | |
| SCHEMBL9314455 | 0.74 | HDAC6 (0.48) | HDAC6KDM4EGAASMN1; SMN2MPO | |
| SCHEMBL3516889 | 0.73 | CA1 (0.50) | KDM4ELMNATDP1FFAR1ALDH1A1 | |
| SCHEMBL21935596 | 0.73 | FFAR1 (0.43) | KDM4EGAALMNATDP1FFAR1 | |
| SCHEMBL21935867 | 0.73 | FFAR1 (0.43) | KDM4EGAALMNATDP1FFAR1 | |
| SCHEMBL29385781 | 0.73 | CA1 (0.50) | KDM4ELMNATDP1FFAR1ALDH1A1 | |
| SCHEMBL11076587 | 0.73 | KDM4E (0.48) | HDAC6KDM4EGAALMNATDP1 | |
| SCHEMBL7585759 | 0.72 | HDAC6 (0.38) | HDAC6KDM4EGAALMNATDP1 | |
| SCHEMBL21061225 | 0.71 | CYP3A4 (0.58) | KDM4ELMNATDP1FFAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4448730-A | ANTITUMOR AGENTS | RIET BARTHOLOMEUS VAN T | 1984-05-15 | — | — | US | disclosed |