Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11076742 | 1.00 | MAPT (0.37) | MAPTHIF1AKDM1AHSD11B1NPC1 | |
| SCHEMBL1235852 | 0.67 | MAPT (0.68) | MAPTHIF1AHSD11B1NPC1EPHX1 | |
| SCHEMBL3397911 | 0.67 | MAPT (0.62) | MAPTHIF1AKDM1AHSD11B1NPC1 | |
| SCHEMBL22607746 | 0.65 | KDM4E (0.37) | HIF1AHSD11B1NPC1EPHX1RAB9A | |
| SCHEMBL1237586 | 0.64 | MAPT (0.70) | MAPTHIF1ARAB9A | |
| SCHEMBL20373921 | 0.64 | NOS1 (0.38) | — | |
| SCHEMBL11071014 | 0.63 | KDM1A (0.35) | MAPTKDM1A | |
| SCHEMBL10653494 | 0.63 | PARP1 (0.32) | — | |
| SCHEMBL10653501 | 0.63 | PARP1 (0.32) | — | |
| SCHEMBL11071002 | 0.63 | KDM1A (0.35) | MAPTKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10005947-B2 | Modified hydrocarbon resins as fluid loss additives | INGEVITY SOUTH CAROLINA, LLC (US) | 2018-06-26 | — | — | US | disclosed |
| US-20150136402-A1 | MODIFIED HYDROCARBON RESINS AS FLUID LOSS ADDITIVES | GEORGIA-PACIFIC CHEMICALS LLC (US) | 2015-05-21 | — | — | US | disclosed |
| US-4433100-A | DICYCLOPENTADIENE, NON-AROMATIC UNSATURATED HYDROCARBON, FATTY OR ROSIN ACID | NEVILLE CHEMICAL COMPANY (US) | 1984-02-21 | — | — | US | disclosed |