Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 5/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | KDM5A | P29375 | 3/20 | 0.38 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.38 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11075218 | 1.00 | SIGMAR1 (0.39) | SIGMAR1EPHX1NAAACYP4F2CYP4A11 | |
| SCHEMBL11068963 | 1.00 | SIGMAR1 (0.39) | SIGMAR1EPHX1NAAACYP4F2CYP4A11 | |
| SCHEMBL11076593 | 0.99 | SIGMAR1 (0.41) | SIGMAR1EPHX1NAAAKDM5APHF8 | |
| SCHEMBL11077308 | 0.99 | SIGMAR1 (0.41) | SIGMAR1EPHX1NAAAKDM5APHF8 | |
| SCHEMBL11075681 | 0.99 | SIGMAR1 (0.41) | SIGMAR1EPHX1NAAAKDM5APHF8 | |
| SCHEMBL11071161 | 0.99 | SIGMAR1 (0.41) | SIGMAR1EPHX1NAAAKDM5APHF8 | |
| SCHEMBL11070926 | 0.97 | EPHX1 (0.41) | SIGMAR1EPHX1NAAA | |
| SCHEMBL11077066 | 0.97 | CYP4F2 (0.38) | SIGMAR1EPHX1NAAACYP4F2CYP4A11 | |
| SCHEMBL11073629 | 0.97 | EPHX1 (0.41) | SIGMAR1EPHX1NAAA | |
| SCHEMBL11076567 | 0.97 | EPHX1 (0.41) | SIGMAR1EPHX1NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4430339-A | PROPHYLAXIS, METABOLISM, GLUCOSE, FATS, HYPOGLYCEMIC AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1984-02-07 | — | — | US | disclosed |
| WO-1982000822-A1 | SUBSTITUTED OXIRANECARBOXYLIC ACIDS,THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | EISTETTER K | 1982-03-18 | — | — | WO | disclosed |