Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.70 |
| ▸ | PRNP | P04156 | 1/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.70 |
| ▸ | PPARG | P37231 | 1/20 | 0.70 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.70 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.70 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.70 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.70 |
| ▸ | GPR17 | Q13304 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11086577 | 0.99 | NPSR1 (0.68) | NPSR1PRNPCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1343751 | 0.92 | RXFP1 (0.67) | NPSR1PRNPCYP1A2CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL4785906 | 0.91 | RXFP1 (0.65) | NPSR1PRNPCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL26978823 | 0.89 | GPR17 (0.75) | NPSR1PRNPCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL12133144 | 0.86 | PPARG (0.79) | NPSR1PRNPCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL16516496 | 0.83 | POLB (0.60) | GPR17ALDH1A1KDM4EMAPTPOLB | |
| SCHEMBL1894184 | 0.82 | RXFP1 (1.00) | NPSR1PRNPCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9449320 | 0.82 | PRNP (0.74) | NPSR1PRNPCYP1A2CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL11080678 | 0.81 | HTR6 (0.68) | NPSR1PRNPCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5634953 | 0.81 | HTR1D (0.58) | NPSR1PRNPCYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4456607-A | 9-Bromo-hexahydro- and octahydro-indolo[2,3 a]quinolizines and use for increasing blood circulation | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1984-06-26 | — | — | US | disclosed |
| US-4428877-A | VASODILATORS | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1984-01-31 | — | — | US | disclosed |
| US-4315011-A | VASODILATORS | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1982-02-09 | — | — | US | disclosed |