Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 9/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11081234 | 0.86 | EPHX1 (0.36) | EPHX1ALDH1A1EPHX2 | |
| SCHEMBL11079386 | 0.74 | EPHX1 (0.41) | EPHX1NPSR1ALDH1A1RAB9A | |
| SCHEMBL11255902 | 0.74 | EPHX1 (0.41) | EPHX1NPSR1ALDH1A1RAB9A | |
| SCHEMBL11073548 | 0.74 | EPHX1 (0.41) | EPHX1NPSR1ALDH1A1RAB9A | |
| SCHEMBL11258826 | 0.73 | ALDH1A1 (0.54) | EPHX1ALDH1A1 | |
| SCHEMBL11262630 | 0.72 | EPHX1 (0.39) | EPHX1ALDH1A1 | |
| SCHEMBL11262635 | 0.72 | EPHX1 (0.39) | EPHX1ALDH1A1 | |
| SCHEMBL11497472 | 0.72 | MEN1 (0.41) | ALDH1A1 | |
| Cyclopentanamine SCHEMBL11079380 | 0.70 | EPHX1 (0.38) | EPHX1 | |
| SCHEMBL11102914 | 0.69 | HRH3 (0.38) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0026369-B1 | CARBAMATES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BASF Aktiengesellschaft (DE) | 1984-08-08 | — | — | EP | disclosed |
| US-4335138-A | HYPNOTIC, SEDATIVE | BASF AKTIENGESELLSCHAFT (DE) | 1982-06-15 | — | — | US | disclosed |
| EP-0026369-A2 | Carbamates, their preparation and pharmaceutical compositions containing them | BASF Aktiengesellschaft (DE) | 1981-04-08 | — | — | EP | disclosed |