Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.41 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.35 |
| ▸ | REN | P00797 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11077539 | 0.89 | SLC6A9 (0.41) | SLC6A9SLC6A5TSHRHPGDSLC6A2 | |
| SCHEMBL7277305 | 0.89 | SLC6A9 (0.42) | SLC6A9SLC6A5TSHRHPGDSLC6A2 | |
| SCHEMBL13001234 | 0.88 | TSHR (0.40) | SLC6A9SLC6A5TSHRHPGDSLC6A2 | |
| SCHEMBL11083435 | 0.84 | SLC6A9 (0.45) | SLC6A9SLC6A5TSHRHPGDSLC6A2 | |
| SCHEMBL7278211 | 0.81 | SLC6A9 (0.41) | SLC6A9SLC6A5TSHRHPGDSLC6A2 | |
| SCHEMBL7277297 | 0.80 | SLC6A9 (0.41) | SLC6A9SLC6A5TSHRHPGDSLC6A2 | |
| SCHEMBL7287646 | 0.79 | MEN1 (0.42) | SLC6A9SLC6A5TSHRSLC6A2SLC6A4 | |
| SCHEMBL13001257 | 0.77 | TSHR (0.39) | SLC6A9SLC6A5TSHRALDH1A1HTT | |
| SCHEMBL7278204 | 0.76 | SLC6A9 (0.36) | SLC6A9SLC6A5TSHRHPGDSLC6A2 | |
| SCHEMBL11083431 | 0.73 | SLC6A9 (0.45) | SLC6A9SLC6A5TSHRHPGDSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4479950-A | Aroylaminoacid disulfides | USV PHARMACEUTICAL CORPORATION (US) | 1984-10-30 | — | — | US | disclosed |
| US-4347246-A | Antihypertensive lactams | USV PHARMACEUTICAL CORPORATION (US) | 1982-08-31 | — | — | US | disclosed |