Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 5/20 | 0.64 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.64 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.63 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.63 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.63 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.63 |
| ▸ | DRD1 | P21728 | 2/20 | 0.63 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.63 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.63 |
| ▸ | MMP1 | P03956 | 1/20 | 0.63 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.63 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.63 |
| ▸ | HTR1A | P08908 | 1/20 | 0.63 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.63 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.63 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.63 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.63 |
| ▸ | HRH2 | P25021 | 1/20 | 0.63 |
| ▸ | TACR1 | P25103 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11077667 | 1.00 | ADRA1A (0.64) | ADRA1AADRA1BADRA1DADRA2AADRA2B | |
| SCHEMBL11081769 | 0.95 | KDM4E (0.64) | ADRA1AADRA1BADRA1DADRA2AADRA2B | |
| SCHEMBL11085528 | 0.95 | KDM4E (0.64) | ADRA1AADRA1BADRA1DADRA2AADRA2B | |
| SCHEMBL11081772 | 0.95 | KDM4E (0.64) | ADRA1AADRA1BADRA1DADRA2AADRA2B | |
| SCHEMBL11085532 | 0.95 | KDM4E (0.64) | ADRA1AADRA1BADRA1DADRA2AADRA2B | |
| SCHEMBL11081436 | 0.94 | ADRA1A (0.64) | ADRA1AADRA1BADRA1DADRA2AADRA2B | |
| SCHEMBL11088427 | 0.94 | ADRA1A (0.64) | ADRA1AADRA1BADRA1DADRA2AADRA2B | |
| SCHEMBL11081432 | 0.94 | ADRA1A (0.64) | ADRA1AADRA1BADRA1DADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL11091781 | 0.93 | ADRA1A (0.62) | ADRA1AADRA1BADRA1DADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL11091779 | 0.93 | ADRA1A (0.62) | ADRA1AADRA1BADRA1DADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4426382-A | HYPOTENSIVE AGENTS | SANKYO COMPANY LIMITED (JP) | 1984-01-17 | — | — | US | disclosed |