Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.49 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.49 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | OGG1 | O15527 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10874670 | 0.87 | CYP11B1 (0.44) | CYP11B1CYP11B2CYP19A1CYP2A6CYP2B6 | |
| SCHEMBL8638509 | 0.86 | TP53 (0.47) | CYP11B1CYP11B2CYP19A1CYP2A6CYP2B6 | |
| SCHEMBL10505778 | 0.81 | CYP11B1 (0.56) | CYP11B1CYP11B2CYP19A1CYP2A6CYP2B6 | |
| SCHEMBL9201200 | 0.81 | CYP11B1 (0.56) | CYP11B1CYP11B2CYP19A1CYP2A6CYP2B6 | |
| Hydrochloric Acid SCHEMBL10877343 | 0.81 | OGG1 (0.57) | PTGS2OGG1TSHRADRA2C | |
| SCHEMBL8376654 | 0.80 | CYP11B1 (0.39) | CYP11B1CYP11B2CYP19A1CYP2A6CYP2B6 | |
| SCHEMBL8380189 | 0.80 | CYP11B1 (0.39) | CYP11B1CYP11B2CYP19A1CYP2A6CYP2B6 | |
| SCHEMBL8380173 | 0.80 | CYP11B1 (0.39) | CYP11B1CYP11B2CYP19A1CYP2A6CYP2B6 | |
| SCHEMBL11076363 | 0.79 | CYP11B1 (0.50) | CYP11B1CYP11B2CYP19A1CYP2A6CYP2B6 | |
| SCHEMBL11083928 | 0.79 | CYP11B1 (0.50) | CYP11B1CYP11B2CYP19A1CYP2A6CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4432989-A | αAryl-1H-imidazole-1-ethanols | SANDOZ, INC. (US) | 1984-02-21 | — | — | US | disclosed |