SCHEMBL11077973

SCHEMBL11077973

C=CCNC(=O)OCC1(C(C)=O)CC2C=CC1C2

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.34
KMT2A Q03164 3/20 0.33
MEN1 O00255 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
NPSR1 Q6W5P4 1/20 0.32
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11260303 1.00 ALDH1A1 (0.34) ALDH1A1KMT2AMEN1L3MBTL1NPSR1
SCHEMBL11251554 0.88 MEN1 (0.36) ALDH1A1KMT2AMEN1L3MBTL1
SCHEMBL11074365 0.87 ALDH1A1 (0.33) ALDH1A1KMT2AMEN1L3MBTL1
SCHEMBL11074362 0.87 ALDH1A1 (0.33) ALDH1A1KMT2AMEN1L3MBTL1
SCHEMBL11249821 0.85 ALDH1A1 (0.30) ALDH1A1
SCHEMBL11077566 0.85 ALDH1A1 (0.30) ALDH1A1
SCHEMBL11102700 0.85 ALDH1A1 (0.49) ALDH1A1KMT2AMEN1L3MBTL1
SCHEMBL11072565 0.83 ALDH1A1 (0.35) ALDH1A1KMT2AMEN1L3MBTL1
SCHEMBL11252003 0.83 MEN1 (0.39) ALDH1A1KMT2AMEN1L3MBTL1
SCHEMBL11252005 0.83 MEN1 (0.39) ALDH1A1KMT2AMEN1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0026369-B1 CARBAMATES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM BASF Aktiengesellschaft (DE) 1984-08-08 EP disclosed
US-4335138-A HYPNOTIC, SEDATIVE BASF AKTIENGESELLSCHAFT (DE) 1982-06-15 US disclosed
EP-0026369-A2 Carbamates, their preparation and pharmaceutical compositions containing them BASF Aktiengesellschaft (DE) 1981-04-08 EP disclosed