Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11080638 | 0.78 | POLB (0.47) | CES2CES1ALDH1A1POLBKMT2A | |
| SCHEMBL344758 | 0.77 | USP2 (0.55) | CES2CES1ALDH1A1USP2POLB | |
| SCHEMBL8875219 | 0.77 | TSHR (0.47) | CES2CES1ALDH1A1USP2POLB | |
| Hydrochloric Acid SCHEMBL1653611 | 0.76 | TSHR (0.46) | CES2CES1ALDH1A1USP2 | |
| SCHEMBL11242713 | 0.73 | TSHR (0.43) | CES2CES1ALDH1A1USP2 | |
| SCHEMBL27773972 | 0.72 | CES2 (0.46) | CES2CES1ALDH1A1USP2POLB | |
| SCHEMBL2585991 | 0.70 | CES2 (0.52) | CES2CES1ALDH1A1POLBKMT2A | |
| Hydrochloric Acid SCHEMBL10841241 | 0.69 | PDCD1 (0.44) | ALDH1A1KMT2ANPC1RAB9ARECQL | |
| SCHEMBL16893390 | 0.69 | TSHR (0.46) | CES2CES1ALDH1A1USP2KMT2A | |
| SCHEMBL21842893 | 0.69 | PDCD1 (0.44) | KMT2ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4431667-A | Imino ethers useful for controlling insect and arachnoid pests | THE UPJOHN COMPANY (US) | 1984-02-14 | — | — | US | disclosed |
| US-4357347-A | INSECTICIDES, INSECT GROWTH REGULATORS | THE UPJOHN COMPANY (US) | 1982-11-02 | — | — | US | disclosed |