Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | ESR1 | P03372 | 2/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3174222 | 0.92 | MAPT (0.55) | MAPTGAAALDH1A1ESR1ESR2 | |
| SCHEMBL28545151 | 0.83 | MAPT (0.54) | MAPTGAAALDH1A1ESR1LMNA | |
| Acetic Acid SCHEMBL28545152 | 0.82 | MAPT (0.65) | MAPTGAAALDH1A1ESR1ESR2 | |
| SCHEMBL2024527 | 0.79 | MAPT (0.61) | MAPTGAAALDH1A1ESR1ESR2 | |
| SCHEMBL11207630 | 0.79 | ESR1 (0.53) | MAPTGAAALDH1A1ESR1ESR2 | |
| SCHEMBL31116643 | 0.79 | MAPT (0.60) | MAPTGAAALDH1A1LMNAHTT | |
| SCHEMBL2024967 | 0.79 | MAPT (0.60) | MAPTGAAALDH1A1LMNAHTT | |
| SCHEMBL9195639 | 0.79 | HTT (0.54) | MAPTGAAALDH1A1ESR1ESR2 | |
| SCHEMBL24194100 | 0.78 | MAPT (0.50) | MAPTGAAALDH1A1ESR1ESR2 | |
| SCHEMBL31315023 | 0.78 | MAPT (0.50) | MAPTGAAALDH1A1ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4460681-A | COLOR FORMING LAYERS, AND SOLVENT SOLUBLE BARRIE LAYERS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1984-07-17 | — | — | US | disclosed |