Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 3/20 | 0.52 |
| ▸ | ADH1C | P00326 | 2/20 | 0.50 |
| ▸ | ADH1A | P07327 | 2/20 | 0.50 |
| ▸ | ADH4 | P08319 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | ADH1B | P00325 | 1/20 | 0.41 |
| ▸ | ADH7 | P40394 | 1/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | GGPS1 | O95749 | 3/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL303315 | 1.00 | DNM1 (0.52) | DNM1ADH1CADH1AADH4TSHR | |
| SCHEMBL77300 | 1.00 | DNM1 (0.52) | DNM1ADH1CADH1AADH4TSHR | |
| SCHEMBL11077987 | 1.00 | DNM1 (0.52) | DNM1ADH1CADH1AADH4TSHR | |
| SCHEMBL1721710 | 1.00 | DNM1 (0.52) | DNM1ADH1CADH1AADH4TSHR | |
| SCHEMBL303397 | 1.00 | DNM1 (0.52) | DNM1ADH1CADH1AADH4TSHR | |
| SCHEMBL6152969 | 1.00 | DNM1 (0.52) | DNM1ADH1CADH1AADH4TSHR | |
| SCHEMBL303801 | 1.00 | DNM1 (0.52) | DNM1ADH1CADH1AADH4TSHR | |
| SCHEMBL9660379 | 1.00 | DNM1 (0.52) | DNM1ADH1CADH1AADH4TSHR | |
| SCHEMBL1061739 | 1.00 | DNM1 (0.52) | DNM1ADH1CADH1AADH4TSHR | |
| SCHEMBL303288 | 1.00 | DNM1 (0.52) | DNM1ADH1CADH1AADH4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0050790-B1 | PREPARATION OF ALPHA-CHLORINATED NITROGEN HETEROCYCLES | BAYER AG (DE) | 1984-12-19 | — | — | EP | disclosed |
| EP-0050790-A1 | Preparation of alpha-chlorinated nitrogen heterocycles | BAYER AG (DE) | 1982-05-05 | — | — | EP | disclosed |