Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 6/20 | 0.47 |
| ▸ | MAP3K5 | Q99683 | 2/20 | 0.47 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 5/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | PRKACA | P17612 | 1/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.42 |
| ▸ | MARK3 | P27448 | 1/20 | 0.42 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.42 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.42 |
| ▸ | MARK2 | Q7KZI7 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9203283 | 0.77 | HTT (0.76) | HTTMAP3K5NCOA1SMN1; SMN2NCOA3 | |
| SCHEMBL11078110 | 0.75 | SLC29A1 (0.44) | HTTMAP3K5SMN1; SMN2LMNATSHR | |
| SCHEMBL9096944 | 0.66 | HSD17B10 (0.69) | HTTMAP3K5NCOA1SMN1; SMN2NCOA3 | |
| SCHEMBL2741119 | 0.65 | TDP1 (0.64) | HTTSMN1; SMN2HSD17B10LMNATSHR | |
| SCHEMBL9203099 | 0.64 | HTT (0.62) | HTTMAP3K5NCOA1SMN1; SMN2NCOA3 | |
| SCHEMBL6747380 | 0.63 | CHEK1 (0.56) | SMN1; SMN2CDK2PDPK1CHEK1AURKA | |
| SCHEMBL401117 | 0.63 | PDPK1 (0.59) | MAP3K5CDK2PDPK1CHEK1AURKA | |
| SCHEMBL9705707 | 0.63 | CDK2 (0.56) | HTTMAP3K5NCOA1SMN1; SMN2NCOA3 | |
| SCHEMBL8826213 | 0.62 | TDP1 (0.40) | AURKAHSD17B10TSHRALDH1A1 | |
| SCHEMBL16146779 | 0.61 | CDK1 (0.41) | HTTMAP3K5CDK2PDPK1CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447582-A | QUATERNIZATION, CROSSLINKING | COPOLYMER RUBBER & CHEMICAL CORPORATION (US) | 1984-05-08 | — | — | US | claimed |
| US-4447582-A | QUATERNIZATION, CROSSLINKING | COPOLYMER RUBBER & CHEMICAL CORPORATION (US) | 1984-05-08 | — | — | US | disclosed |