Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5180007 | 0.84 | KMT2A (0.51) | KDM4EALDH1A1GAAEGFRSMN1; SMN2 | |
| SCHEMBL8106601 | 0.80 | KMT2A (0.42) | KDM4EALDH1A1GAAHPGDMAPT | |
| SCHEMBL5179199 | 0.79 | GRIN2D (0.45) | KDM4EALDH1A1GAAGLAEGFR | |
| SCHEMBL3171866 | 0.78 | KDM4E (0.45) | KDM4EALDH1A1GAAGLASMN1; SMN2 | |
| SCHEMBL9094208 | 0.76 | GABRA1 (0.48) | KDM4EALDH1A1GAAHPGDMAPT | |
| SCHEMBL28357703 | 0.76 | CYP4F2 (0.40) | KDM4EALDH1A1GAAGLAEGFR | |
| SCHEMBL11075684 | 0.75 | KDM4E (0.49) | KDM4EALDH1A1GAAHPGDMAPT | |
| SCHEMBL8147897 | 0.74 | GABRA1 (0.52) | KDM4EALDH1A1GAAGLAEGFR | |
| SCHEMBL3174185 | 0.73 | SMN1; SMN2 (0.40) | KDM4EALDH1A1GAAEGFRSMN1; SMN2 | |
| SCHEMBL16111196 | 0.72 | SMN1; SMN2 (0.39) | KDM4EALDH1A1GAAEGFRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0120669-A2 | Hydroxypyridones, and their pharmaceutical compositions | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1984-10-03 | — | — | EP | disclosed |
| EP-0120670-A1 | Iron III complexes of hydroxypyridones, and their pharmaceutical compositions | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1984-10-03 | — | — | EP | disclosed |