Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.52 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.52 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.52 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | SLC15A2 | Q16348 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11078730 | 1.00 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1MAPTSLC22A6SLC22A8 | |
| SCHEMBL11081854 | 0.90 | MAPT (0.48) | ALDH1A1L3MBTL1MAPTSLC22A6SLC22A8 | |
| SCHEMBL11078002 | 0.89 | MAPT (0.51) | ALDH1A1L3MBTL1MAPTSLC22A6SLC22A8 | |
| SCHEMBL11078000 | 0.89 | MAPT (0.51) | ALDH1A1L3MBTL1MAPTSLC22A6SLC22A8 | |
| SCHEMBL11076190 | 0.88 | MAPT (0.61) | ALDH1A1MAPTSLC22A6SLC22A8PDE3A | |
| SCHEMBL11076195 | 0.88 | MAPT (0.61) | ALDH1A1MAPTSLC22A6SLC22A8PDE3A | |
| SCHEMBL11082683 | 0.86 | MAPT (0.52) | ALDH1A1L3MBTL1MAPTSLC22A6SLC22A8 | |
| SCHEMBL11082688 | 0.86 | MAPT (0.52) | ALDH1A1L3MBTL1MAPTSLC22A6SLC22A8 | |
| SCHEMBL11583071 | 0.86 | ALDH1A1 (0.69) | ALDH1A1L3MBTL1MAPTSLC22A6SLC22A8 | |
| SCHEMBL11583073 | 0.86 | ALDH1A1 (0.69) | ALDH1A1L3MBTL1MAPTSLC22A6SLC22A8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4429128-A | CARBAPENICILLINS, THIENAMYCINS, BACTERICIDES | PFIZER INC. (US) | 1984-01-31 | — | — | US | disclosed |
| US-4348264-A | Photocatalyzed process for producing carbapenams and carbapen-2-ems | PFIZER INC. (US) | 1982-09-07 | — | — | US | disclosed |