SCHEMBL11078733

SCHEMBL11078733

COc1ccc(-c2cc(O)ccc2O)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 1/20 0.61
BACE1 P56817 2/20 0.59
GAA P10253 2/20 0.55
NPC1 O15118 3/20 0.55
RAB9A P51151 3/20 0.55
SMN1; SMN2 Q16637 3/20 0.55
TP53 P04637 2/20 0.55
MAPK1 P28482 1/20 0.55
CASP3 P42574 1/20 0.55
SENP8 Q96LD8 1/20 0.55
SENP7 Q9BQF6 1/20 0.55
SENP6 Q9GZR1 1/20 0.55
HSP90AA1 P07900 1/20 0.52
ABL1 P00519 3/20 0.51
ABCB1 P08183 3/20 0.51
BCR P11274 3/20 0.51
KMT2A Q03164 5/20 0.51
MEN1 O00255 4/20 0.51
NOD2 Q9HC29 1/20 0.51
MIF P14174 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29541984 0.88 KMT2A (0.61) ESR2BACE1GAANPC1RAB9A
SCHEMBL16900562 0.88 ESR2 (0.72) ESR2BACE1GAANPC1RAB9A
SCHEMBL1847771 0.86 GAA (0.65) ESR2BACE1GAANPC1RAB9A
SCHEMBL10579363 0.86 ESR2 (0.60) ESR2BACE1GAANPC1RAB9A
1,4-Dimethoxybenzene SCHEMBL7460138 0.84 BACE1 (0.59) ESR2BACE1GAANPC1RAB9A
SCHEMBL13861252 0.83 PELI1 (0.53) ESR2BACE1GAANPC1ABL1
SCHEMBL7775876 0.83 ESR2 (0.59) ESR2BACE1GAANPC1RAB9A
SCHEMBL7777203 0.81 ESR2 (0.57) ESR2BACE1GAANPC1RAB9A
SCHEMBL6573878 0.81 TDP1 (0.52) ESR2BACE1GAANPC1RAB9A
SCHEMBL7777345 0.81 ESR2 (0.57) ESR2BACE1GAANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103923311-B Side chain type polyether sulphone containing carbazole, preparation method and application JILIN UNIVERSITY (CN) 2016-02-03 CN claimed
CN-103923311-A Carbazole-containing side chain type polyether sulfone, and preparation method and applications UNIV JILIN 2014-07-16 CN claimed
US-4016211-A ARYLHYDROQUINONE STABILIZERS SNAM PROGETTI S.P.A. (IT) 1977-04-05 US claimed
CN-103788365-B A kind of polyarylether and anion-exchange membrane and preparation method thereof containing quaternary ammonium lateral group CHINA PETROLEUM & CHEMICAL CORP. (CN) 2016-02-24 CN disclosed
CN-103923311-B Side chain type polyether sulphone containing carbazole, preparation method and application JILIN UNIVERSITY (CN) 2016-02-03 CN disclosed
CN-103923311-A Carbazole-containing side chain type polyether sulfone, and preparation method and applications UNIV JILIN 2014-07-16 CN disclosed
CN-103788365-A Polyarylether containing quaternary ammonium side group and its preparation method, and anion exchange membrane containing quaternary ammonium side group and its preparation method CHINA PETROLEUM & CHEMICAL 2014-05-14 CN disclosed
US-4460681-A COLOR FORMING LAYERS, AND SOLVENT SOLUBLE BARRIE LAYERS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1984-07-17 US disclosed
EP-0032063-B1 NOVEL SUBSTITUTED ARYLENE COMPOUNDS AND PROCESSES FOR THEIR PRODUCTION WARNER-LAMBERT COMPANY (US) 1984-03-14 EP disclosed
US-4377634-A SENSITIZATION OF SILVER HALIDE EMULSIONS USING AN ARYL HYDRAZIDE AND A HYDROQUIONE; NEGATIVES FUJI PHOTO FILM CO., LTD. (JP) 1983-03-22 US disclosed
US-4351950-A Anti-arteriosclerotic agents WARNER-LAMBERT COMPANY (US) 1982-09-28 US disclosed
EP-0032063-A2 Novel substituted arylene compounds and processes for their production WARNER-LAMBERT COMPANY (US) 1981-07-15 EP disclosed