Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 2/20 | 0.38 |
| ▸ | UGCG | Q16739 | 2/20 | 0.38 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20052999 | 0.83 | TSHR (0.50) | MEN1KMT2ATDP1L3MBTL1TSHR | |
| SCHEMBL11825232 | 0.78 | TSHR (0.42) | MEN1KMT2ATSHRTAAR1DRD2 | |
| SCHEMBL14948695 | 0.77 | SMN1; SMN2 (0.41) | MEN1KMT2ATDP1L3MBTL1TSHR | |
| Bicarbonate SCHEMBL9187058 | 0.75 | BID (0.48) | NAAA | |
| SCHEMBL334897 | 0.72 | MEN1 (0.64) | MEN1KMT2AHRH3HRH4TDP1 | |
| SCHEMBL8951260 | 0.72 | MEN1 (0.41) | MEN1KMT2ATDP1TSHRTAAR1 | |
| SCHEMBL16796644 | 0.72 | HRH4 (0.48) | KMT2AHRH3HRH4TDP1L3MBTL1 | |
| SCHEMBL4069939 | 0.72 | TDP1 (0.64) | MEN1KMT2AHRH3HRH4TDP1 | |
| SCHEMBL334794 | 0.71 | MEN1 (0.62) | MEN1KMT2AHRH3HRH4TDP1 | |
| SCHEMBL379442 | 0.71 | CYSLTR2 (0.50) | MEN1KMT2ATDP1TSHRDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0099692-A1 | New furanone derivatives, process for the preparation thereof and use thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-02-01 | — | — | EP | disclosed |