Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL9187058 | 0.82 | BID (0.48) | — | |
| SCHEMBL11078799 | 0.78 | MEN1 (0.48) | TSHRDRD2MEN1KMT2ATAAR1 | |
| SCHEMBL20052999 | 0.77 | TSHR (0.50) | TSHRHTR1ADRD2MEN1KMT2A | |
| SCHEMBL8951260 | 0.75 | MEN1 (0.41) | TSHRHTR1AMEN1KMT2AALDH1A1 | |
| SCHEMBL7049394 | 0.75 | TSHR (0.41) | TSHRALDH1A1TAAR1 | |
| SCHEMBL8358228 | 0.75 | CTSB (0.49) | TSHRMEN1KMT2A | |
| SCHEMBL31503923 | 0.75 | TSHR (0.41) | TSHRALDH1A1TAAR1 | |
| SCHEMBL28260280 | 0.75 | TSHR (0.41) | TSHR | |
| SCHEMBL2307568 | 0.74 | CYSLTR2 (0.50) | TSHRDRD2MEN1KMT2ANR1H2 | |
| SCHEMBL379442 | 0.74 | CYSLTR2 (0.50) | TSHRDRD2MEN1KMT2ANR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3975279-A | B-(HALOPROPYL)-THIONOPHOSPHATE AND A STYRENE OXIDE | ETHYL CORPORATION (US) | 1976-08-17 | — | — | US | disclosed |