Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | UBE2N | P61088 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11088024 | 0.81 | KMT2A (0.41) | KMT2ASMN1; SMN2POLBSIGMAR1LMNA | |
| SCHEMBL11288373 | 0.81 | KMT2A (0.41) | KMT2ASMN1; SMN2POLBDRD3KCNH2 | |
| SCHEMBL11083020 | 0.77 | SMN1; SMN2 (0.49) | KMT2ASMN1; SMN2LMNAHTT | |
| SCHEMBL11084383 | 0.77 | KMT2A (0.42) | KMT2ASMN1; SMN2POLBDRD3KCNH2 | |
| SCHEMBL11080635 | 0.75 | KMT2A (0.41) | KMT2ASIGMAR1NPC1APAF1 | |
| SCHEMBL11086432 | 0.72 | DRD3 (0.39) | KMT2ADRD3KCNH2SIGMAR1LMNA | |
| SCHEMBL11079756 | 0.71 | KMT2A (0.47) | KMT2ASMN1; SMN2POLBSIGMAR1LMNA | |
| SCHEMBL11613138 | 0.66 | KMT2A (0.47) | KMT2ASMN1; SMN2POLBDRD3KCNH2 | |
| SCHEMBL8924899 | 0.66 | DRD3 (0.60) | KMT2ASMN1; SMN2POLBDRD3KCNH2 | |
| SCHEMBL11085022 | 0.66 | KMT2A (0.40) | KMT2ASMN1; SMN2POLBLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4426522-A | ANTICOCCIDIAL | ABIC LTD. (IL) | 1984-01-17 | — | — | US | disclosed |
| EP-0058534-A2 | Hexahydro-1,2,4-triazine-3,5-dione derivatives and their use as feed additives | ABIC LTD. (IL) | 1982-08-25 | — | — | EP | disclosed |