Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | DBH | P09172 | 1/20 | 0.42 |
| ▸ | APAF1 | O14727 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11081247 | 0.84 | KMT2A (0.44) | KMT2ASIGMAR1DBHALDH1A1MAPT | |
| SCHEMBL11082068 | 0.83 | KMT2A (0.43) | KMT2ASIGMAR1DBHALDH1A1MAPT | |
| SCHEMBL11089788 | 0.81 | MAPT (0.51) | KMT2ASMN1; SMN2SIGMAR1DBHCYP1A2 | |
| SCHEMBL11075283 | 0.80 | SMN1; SMN2 (0.45) | KMT2ASMN1; SMN2POLBALDH1A1TP53 | |
| SCHEMBL11084167 | 0.76 | USP2 (0.43) | KMT2ASMN1; SMN2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL11079280 | 0.75 | KMT2A (0.51) | KMT2ASMN1; SMN2POLBALDH1A1TP53 | |
| SCHEMBL11290437 | 0.75 | DBH (0.43) | KMT2ASMN1; SMN2POLBSIGMAR1DBH | |
| SCHEMBL11285216 | 0.74 | SMN1; SMN2 (0.49) | KMT2ASMN1; SMN2POLBSIGMAR1ALDH1A1 | |
| SCHEMBL11079219 | 0.71 | KMT2A (0.44) | KMT2ASMN1; SMN2POLBSIGMAR1APAF1 | |
| SCHEMBL11073959 | 0.71 | KMT2A (0.41) | KMT2ASMN1; SMN2POLBSIGMAR1DBH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0058534-A2 | Hexahydro-1,2,4-triazine-3,5-dione derivatives and their use as feed additives | ABIC LTD. (IL) | 1982-08-25 | — | — | EP | claimed |
| US-4426522-A | ANTICOCCIDIAL | ABIC LTD. (IL) | 1984-01-17 | — | — | US | disclosed |
| EP-0058534-A2 | Hexahydro-1,2,4-triazine-3,5-dione derivatives and their use as feed additives | ABIC LTD. (IL) | 1982-08-25 | — | — | EP | disclosed |