Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.49 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | FDPS | P14324 | 2/20 | 0.41 |
| ▸ | IDH1 | O75874 | 1/20 | 0.41 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.40 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10876268 | 0.87 | NOS1 (0.49) | CYP19A1CYP11B1CYP11B2POLBFDPS | |
| SCHEMBL11077114 | 0.87 | CYP11B1 (0.50) | CYP19A1CYP11B1CYP11B2POLBFDPS | |
| SCHEMBL11083928 | 0.86 | CYP11B1 (0.50) | CYP19A1CYP11B1CYP11B2LMNA | |
| SCHEMBL11085080 | 0.85 | CYP11B1 (0.62) | CYP19A1CYP11B1CYP11B2CYP17A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL10876960 | 0.84 | CYP11B1 (0.48) | CYP19A1CYP11B1CYP11B2POLBFDPS | |
| Hydrochloric Acid SCHEMBL10875434 | 0.84 | CYP11B1 (0.49) | CYP19A1CYP11B1CYP11B2LMNA | |
| Hydrochloric Acid SCHEMBL10877264 | 0.84 | CYP11B1 (0.60) | CYP19A1CYP11B1CYP11B2CYP17A1CYP3A4 | |
| SCHEMBL10514749 | 0.83 | KMT2A (0.42) | CYP19A1CYP11B1CYP11B2CYP17A1CYP3A4 | |
| SCHEMBL11079383 | 0.83 | MEN1 (0.49) | CYP19A1CYP11B1CYP11B2CYP3A4POLB | |
| SCHEMBL11082150 | 0.83 | QPCT (0.44) | CYP19A1CYP11B1CYP11B2CYP17A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4432989-A | αAryl-1H-imidazole-1-ethanols | SANDOZ, INC. (US) | 1984-02-21 | — | — | US | disclosed |