Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | FNTA | P49354 | 2/20 | 0.45 |
| ▸ | FNTB | P49356 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | BCL9 | O00512 | 1/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11079312 | 1.00 | MAPT (0.50) | MAPTGAAALDH1A1KDM4EGLA | |
| SCHEMBL913460 | 0.92 | GAA (0.47) | MAPTGAAALDH1A1CASP1FNTA | |
| SCHEMBL974922 | 0.87 | FNTA (0.52) | MAPTGAAALDH1A1FNTAFNTB | |
| SCHEMBL29229939 | 0.85 | EPHX2 (0.51) | MAPTGAAALDH1A1KDM4EHPGD | |
| SCHEMBL27303322 | 0.85 | EPHX2 (0.51) | MAPTGAAALDH1A1KDM4EHPGD | |
| SCHEMBL9046932 | 0.85 | EPHX2 (0.51) | MAPTGAAALDH1A1KDM4EHPGD | |
| SCHEMBL18095168 | 0.85 | MGLL (0.51) | MAPTGAAALDH1A1FNTAFNTB | |
| SCHEMBL18211946 | 0.84 | GAA (0.54) | MAPTGAAALDH1A1KDM4EGLA | |
| SCHEMBL27857345 | 0.83 | HDAC1 (0.55) | FNTAFNTB | |
| SCHEMBL11085230 | 0.83 | GAA (0.53) | MAPTGAAALDH1A1KDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482495-A | CHEMICAL INTERMEDIATES FOR ANALGESICS | STERLING DRUG INC. (US) | 1984-11-13 | — | — | US | disclosed |
| US-4405800-A | ANALGESICS | STERLING DRUG INC. (US) | 1983-09-20 | — | — | US | disclosed |
| US-4361703-A | ANALGESICS | STERLING DRUG INC. (US) | 1982-11-30 | — | — | US | disclosed |
| US-4181719-A | Analgesic N-acetyl-para-aminophenyl N'-acetylaminothioalkanoates | STERLING DRUG INC. (US) | 1980-01-01 | — | — | US | disclosed |