Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11073770 | 0.95 | OPRM1 (0.37) | OPRM1SLC6A4SLC6A2OPRD1OPRK1 | |
| SCHEMBL11076119 | 0.91 | OPRM1 (0.40) | OPRM1SLC6A4DRD3 | |
| SCHEMBL11081052 | 0.91 | OPRM1 (0.38) | OPRM1SLC6A4SLC6A2OPRD1OPRK1 | |
| SCHEMBL11074113 | 0.89 | OPRM1 (0.42) | OPRM1OPRD1OPRK1DRD2DRD3 | |
| SCHEMBL11065461 | 0.88 | OPRM1 (0.37) | OPRM1SLC6A4SLC6A2OPRD1OPRK1 | |
| SCHEMBL11065457 | 0.83 | OPRM1 (0.36) | OPRM1SLC6A4SLC6A2OPRD1OPRK1 | |
| SCHEMBL11075993 | 0.80 | OPRM1 (0.43) | OPRM1SLC6A4SLC6A2OPRD1OPRK1 | |
| SCHEMBL11079389 | 0.80 | OPRM1 (0.38) | OPRM1SLC6A4SLC6A2OPRD1OPRK1 | |
| SCHEMBL11076285 | 0.79 | OPRM1 (0.41) | OPRM1SLC6A4SLC6A2OPRD1OPRK1 | |
| SCHEMBL11076126 | 0.77 | DRD3 (0.37) | OPRM1SLC6A4OPRD1OPRK1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447454-A | Analgetic compounds, compositions and process of treatment | THE UPJOHN COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4113866-A | ANALGETIC COMPOUNDS, COMPOSITIONS AND PROCESS OF TREATMENT | THE UPJOHN COMPANY (US) | 1978-09-12 | — | — | US | disclosed |