SCHEMBL11079397

SCHEMBL11079397

Cc1ccc(-c2nc3ccc(C)cc3c(=O)[nH]2)cc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TNKS O95271 14/20 0.72
TNKS2 Q9H2K2 14/20 0.72
PARP1 P09874 10/20 0.72
RAB9A P51151 3/20 0.58
NPC1 O15118 2/20 0.58
SMN1; SMN2 Q16637 1/20 0.56
TUBB4A P04350 1/20 0.52
TUBB P07437 1/20 0.52
TUBA3C P0DPH7 1/20 0.52
TUBA1B P68363 1/20 0.52
TUBA4A P68366 1/20 0.52
TUBB4B P68371 1/20 0.52
TUBB3 Q13509 1/20 0.52
TUBB2A Q13885 1/20 0.52
TUBB8 Q3ZCM7 1/20 0.52
TUBA3E Q6PEY2 1/20 0.52
TUBA1A Q71U36 1/20 0.52
TUBA1C Q9BQE3 1/20 0.52
TUBB6 Q9BUF5 1/20 0.52
TUBB2B Q9BVA1 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11826929 0.92 TNKS (0.70) TNKSTNKS2PARP1RAB9ANPC1
SCHEMBL1644995 0.91 TNKS (0.66) TNKSTNKS2PARP1RAB9ANPC1
SCHEMBL11083849 0.91 TNKS (0.65) TNKSTNKS2PARP1RAB9ANPC1
SCHEMBL11077586 0.91 TNKS (0.65) TNKSTNKS2PARP1RAB9ANPC1
SCHEMBL11081936 0.88 TNKS (0.70) TNKSTNKS2PARP1RAB9ANPC1
SCHEMBL28948384 0.87 TNKS (0.72) TNKSTNKS2PARP1RAB9ANPC1
SCHEMBL11383332 0.86 TNKS (0.62) TNKSTNKS2PARP1RAB9ANPC1
SCHEMBL7765127 0.84 TNKS (1.00) TNKSTNKS2PARP1RAB9ANPC1
SCHEMBL29764113 0.84 TNKS (1.00) TNKSTNKS2PARP1RAB9ANPC1
SCHEMBL28008970 0.81 TNKS (0.73) TNKSTNKS2PARP1RAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4431440-A 2-/4-METHYLPHENYL/-4-3H-QUINAZOLINES AS HERBICIDES AND PLANT GROWTH REGULATORS; CEREALS AMERICAN CYANAMID COMPANY (US) 1984-02-14 US disclosed
EP-0058822-A1 Method to alter or control the development and/or life cycle of various plant species AMERICAN CYANAMID COMPANY (US) 1982-09-01 EP disclosed