Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 2/20 | 0.34 |
| ▸ | MPO | P05164 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 5/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | GAA | P10253 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALPI | P09923 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8089517 | 0.76 | — | — | |
| SCHEMBL6053111 | 0.73 | — | — | |
| SCHEMBL6053385 | 0.71 | TSHR (0.39) | GFERMAPTALDH1A1KDM4EGAA | |
| SCHEMBL239328 | 0.58 | CTSD (0.63) | CTSDP2RX7GFERMAPTALDH1A1 | |
| SCHEMBL30547074 | 0.58 | CTSD (0.63) | CTSDP2RX7GFERMAPTALDH1A1 | |
| SCHEMBL28723691 | 0.57 | KDM4E (0.44) | CTSDMPOCYP3A4BLMP2RX7 | |
| Benzoic Acid Hydrazide SCHEMBL29222014 | 0.57 | CYP3A4 (0.56) | MPOCYP3A4BLMKDM5AGFER | |
| SCHEMBL20078583 | 0.56 | CYP3A4 (0.62) | MPOCYP3A4BLMKDM5AGFER | |
| Benzoic Acid Hydrazide SCHEMBL4515671 | 0.56 | CYP3A4 (0.62) | MPOCYP3A4BLMKDM5AGFER | |
| Benzoic Acid Hydrazide SCHEMBL83514 | 0.56 | CYP3A4 (0.62) | MPOCYP3A4BLMKDM5AGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0047977-A2 | Cephalosporin derivatives, process for their preparation, pharmaceutical compositions containing them and their use | CIBA-GEIGY AG (CH) | 1982-03-24 | — | — | EP | claimed |
| EP-0121499-A2 | Cephalosporins, their preparation and pharmaceutical compositions | CIBA-GEIGY AG (CH) | 1984-10-10 | — | — | EP | disclosed |
| EP-0092830-A2 | Cephalosporin derivatives, process for their preparation, pharmaceutical compositions containing them and their application | CIBA-GEIGY AG (CH) | 1983-11-02 | — | — | EP | disclosed |
| EP-0076452-A2 | Cephalosporin derivatives, process for their preparation and pharmaceutical compositions containing them | CIBA-GEIGY AG (CH) | 1983-04-13 | — | — | EP | disclosed |
| EP-0047977-A2 | Cephalosporin derivatives, process for their preparation, pharmaceutical compositions containing them and their use | CIBA-GEIGY AG (CH) | 1982-03-24 | — | — | EP | disclosed |