Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | KDR | P35968 | 4/20 | 0.55 |
| ▸ | FLT1 | P17948 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 7/20 | 0.52 |
| ▸ | STAT1 | P42224 | 1/20 | 0.52 |
| ▸ | FBP1 | P09467 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.49 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.49 |
| ▸ | FADS1 | O60427 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11083743 | 0.99 | LMNA (0.55) | LMNATP53MAPTKDRFLT1 | |
| SCHEMBL11084073 | 0.88 | KDR (0.52) | LMNATP53MAPTKDRFLT1 | |
| Hydrochloric Acid SCHEMBL11087813 | 0.87 | KDR (0.51) | LMNATP53MAPTKDRFLT1 | |
| SCHEMBL11090480 | 0.87 | KDM4E (0.66) | LMNAKDRFLT1KDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL11087390 | 0.86 | KDM4E (0.64) | LMNAKDRFLT1KDM4EMEN1 | |
| SCHEMBL11091766 | 0.85 | MAPK1 (0.62) | LMNAMAPTKDRFLT1HTT | |
| SCHEMBL11093822 | 0.84 | TTBK1 (0.60) | LMNATP53MAPTKDRFLT1 | |
| Hydrochloric Acid SCHEMBL11087905 | 0.83 | MAPK1 (0.65) | LMNAMAPTKDRFLT1HTT | |
| Hydrochloric Acid SCHEMBL11084310 | 0.83 | TTBK1 (0.58) | TP53MAPTKDRFLT1HTT | |
| SCHEMBL29236930 | 0.82 | ABCG2 (0.64) | LMNAMAPTKDRFLT1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4464375-A | ANALGESIC, ANTIINFLAMMATORY | SANKYO CO., LTD. (JP) | 1984-08-07 | — | — | US | disclosed |
| US-4322420-A | Method of using 4-anilinoquinazoline derivatives as analgesic and anti-inflammatory agents | SANKYO COMPANY LIMITED (JP) | 1982-03-30 | — | — | US | disclosed |