Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 7/20 | 0.53 |
| ▸ | PDE4B | Q07343 | 7/20 | 0.53 |
| ▸ | PDE4C | Q08493 | 7/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.53 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.49 |
| ▸ | ACVRL1 | P37023 | 8/20 | 0.47 |
| ▸ | ACVR1 | Q04771 | 8/20 | 0.47 |
| ▸ | BMPR1A | P36894 | 7/20 | 0.47 |
| ▸ | BMPR1B | O00238 | 6/20 | 0.47 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.47 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10645730 | 0.95 | PDE3B (0.51) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL11094366 | 0.90 | PDE3B (0.62) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL11091984 | 0.89 | PDE3B (0.55) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL10647530 | 0.88 | PDE3B (0.51) | PDE3BPDE3AACVRL1ACVR1BMPR1A | |
| SCHEMBL11086764 | 0.87 | PDE3B (0.51) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL11090645 | 0.86 | PDE4A (0.48) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL11094260 | 0.85 | PDE4A (0.50) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL11084927 | 0.85 | PDE3B (0.56) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL11093035 | 0.85 | PDE3B (0.65) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL11094425 | 0.83 | PDE4A (0.50) | PDE4APDE4BPDE4CPDE4DPDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4474785-A | HYPOTENSIVE AGENTS, ANTICOAGULANTS | BASF AKTIENGESELLSCHAFT (DE) | 1984-10-02 | — | — | US | disclosed |