Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 2/20 | 0.65 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.65 |
| ▸ | CYP11B1 | P15538 | 9/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 8/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | PDE4A | P27815 | 7/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 7/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 7/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11094366 | 0.95 | PDE3B (0.62) | PDE3BPDE3ACYP11B1CYP11B2CYP1A2 | |
| SCHEMBL11084927 | 0.93 | PDE3B (0.56) | PDE3BPDE3ACYP11B1CYP11B2CYP1A2 | |
| SCHEMBL11090751 | 0.91 | PDE3B (0.65) | PDE3BPDE3ACYP11B1CYP11B2CYP1A2 | |
| SCHEMBL11091984 | 0.90 | PDE3B (0.55) | PDE3BPDE3ACYP11B1CYP11B2CYP1A2 | |
| SCHEMBL10645730 | 0.89 | PDE3B (0.51) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL11079653 | 0.85 | PDE3B (0.48) | PDE3BPDE3ACYP11B1CYP11B2CYP1A2 | |
| SCHEMBL11092270 | 0.85 | PDE3B (0.53) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL11090330 | 0.85 | PDE3B (0.53) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL11080207 | 0.85 | PDE4A (0.53) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL11093394 | 0.84 | PDE3B (0.56) | PDE3BPDE3ACYP11B1CYP11B2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4474785-A | HYPOTENSIVE AGENTS, ANTICOAGULANTS | BASF AKTIENGESELLSCHAFT (DE) | 1984-10-02 | — | — | US | disclosed |